RI

RTW Investments Portfolio holdings

AUM $7.02B
This Quarter Return
-13.4%
1 Year Return
+28.16%
3 Year Return
+245.48%
5 Year Return
+425.65%
10 Year Return
+5,642.23%
AUM
$4.83B
AUM Growth
+$4.83B
Cap. Flow
-$900M
Cap. Flow %
-18.64%
Top 10 Hldgs %
38.68%
Holding
126
New
2
Increased
20
Reduced
30
Closed
20

Top Buys

1
PTGX icon
Protagonist Therapeutics
PTGX
$52M
2
CCCC icon
C4 Therapeutics
CCCC
$49.4M
3
MASI icon
Masimo
MASI
$40.4M
4
CINC
CinCor Pharma, Inc. Common Stock
CINC
$24.4M
5
TSVT
2seventy bio
TSVT
$21M

Top Sells

1
SPY icon
SPDR S&P 500 ETF Trust
SPY
$423M
2
ISEE
IVERIC bio, Inc. Common Stock
ISEE
$112M
3
APLS icon
Apellis Pharmaceuticals
APLS
$98.5M
4
ITOS icon
iTeos Therapeutics
ITOS
$60M
5
IDYA icon
IDEAYA Biosciences
IDYA
$59.6M

Sector Composition

1 Healthcare 99.3%
2 Financials 0.6%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
UTRS
101
DELISTED
Minerva Surgical, Inc. Common Stock
UTRS
$747K 0.02% 166,000 – –
OMIC
102
DELISTED
Singular Genomics Systems, Inc. Common Stock
OMIC
$631K 0.01% 100,000 – –
ADVM icon
103
Adverum Biotechnologies
ADVM
$64.6M
$293K 0.01% 223,725 -7,331,092 -97% -$9.6M
ZY
104
DELISTED
Zymergen Inc. Common Stock
ZY
$202K ﹤0.01% 70,000 – –
RCOR.WS
105
DELISTED
Renovacor, Inc. Warrants, entitling the holder thereof to purchase one-half (1/2) of a share of common stock at a price of $11. 50 per whole share
RCOR.WS
$109K ﹤0.01% 350,000 – –
MSACW
106
DELISTED
Medicus Sciences Acquisition Corp. Warrant
MSACW
$14K ﹤0.01% 33,331 – –
ABUS icon
107
Arbutus Biopharma
ABUS
$711M
– – -2,504,493 Closed -$9.74M
ARWR icon
108
Arrowhead Research
ARWR
$3.05B
– – -346,842 Closed -$23M
BMEA icon
109
Biomea Fusion
BMEA
$116M
– – -593,846 Closed -$4.42M
BOLT icon
110
Bolt Biotherapeutics
BOLT
$9.85M
– – -126,365 Closed -$619K
CLSD icon
111
Clearside Biomedical
CLSD
$28.9M
– – -3,806,018 Closed -$10.5M
IDYA icon
112
IDEAYA Biosciences
IDYA
$2.15B
– – -2,520,076 Closed -$59.6M
INKT icon
113
MiNK Therapeutics
INKT
$64.4M
– – -416,666 Closed -$1.86M
MDXG icon
114
MiMedx Group
MDXG
$1.05B
– – -295,748 Closed -$1.79M
MRUS icon
115
Merus
MRUS
$4.98B
– – -196,231 Closed -$6.24M
NEO icon
116
NeoGenomics
NEO
$1.13B
– – -311,111 Closed -$10.6M
OSUR icon
117
OraSure Technologies
OSUR
$242M
– – -1,154,380 Closed -$10M
SPY icon
118
SPDR S&P 500 ETF Trust
SPY
$658B
– – -889,739 Closed -$423M
SRPT icon
119
Sarepta Therapeutics
SRPT
$1.78B
– – -582,265 Closed -$52.4M
TNGX icon
120
Tango Therapeutics
TNGX
$747M
– – -180,819 Closed -$1.98M
WGS icon
121
GeneDx Holdings
WGS
$3.72B
– – -400,000 Closed -$1.78M
ACHL
122
DELISTED
Achilles Therapeutics plc American Depositary Shares
ACHL
– – -12,229 Closed -$61K
VINC
123
DELISTED
Vincerx Pharma, Inc. Common Stock
VINC
– – -741,236 Closed -$7.55M
CERE
124
DELISTED
Cerevel Therapeutics Holdings, Inc. Common Stock
CERE
– – -666,666 Closed -$21.6M
ISEE
125
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
– – -6,722,624 Closed -$112M
2 3 4
5
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