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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
+60.02%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$5.96B
AUM Growth
+$1.81B
Cap. Flow
+$286M
Cap. Flow %
4.79%
Top 10 Hldgs %
47.57%
Holding
116
New
25
Increased
35
Reduced
12
Closed
14

Top Buys

Rank Stock Value
1
GMED icon
Globus Medical
GMED
+$94.3M
2
TARS icon
Tarsus Pharmaceuticals
TARS
+$70.2M
3
CCCC icon
C4 Therapeutics
CCCC
+$62.3M
4
ARVN icon
Arvinas
ARVN
+$61.8M
5
ILMN icon
Illumina
ILMN
+$61.2M

Sector Composition

Rank Sector Weight
1 Healthcare 94%
2 Financials 0.18%
3 Materials 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
RCKT icon
1
Rocket Pharmaceuticals
RCKT
$355M
$936M 15.7%
17,060,211
+247,720
+1% +$9.03M
IMVT icon
2
Immunovant
IMVT
$8.23B
$351M 5.88%
7,592,253
+81,841
+1% +$3.78M
PTCT icon
3
PTC Therapeutics
PTCT
$6.29B
$258M 4.32%
4,221,836
+228,550
+6% +$13.5M
MRTX
4
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$232M 3.89%
1,054,364
-41,641
-4% -$9M
STOK icon
5
Stoke Therapeutics
STOK
$1.83B
$219M 3.68%
3,544,248
ALNY icon
6
Alnylam Pharmaceuticals
ALNY
$37.2B
$219M 3.67%
1,681,645
NTRA icon
7
Natera
NTRA
$37B
$170M 2.86%
1,712,234
+1,465
+0.1% +$122K
DRNA
8
DELISTED
Dicerna Pharmaceuticals, Inc.
DRNA
$160M 2.68%
7,253,857
+26,444
+0.4% +$582K
ARVN icon
9
Arvinas
ARVN
$530M
$152M 2.55%
+1,790,996
New +$61.8M
VCEL icon
10
Vericel Corp
VCEL
$2.31B
$140M 2.34%
4,517,570
+666,719
+17% +$15.9M
AXSM icon
11
Axsome Therapeutics
AXSM
$12.3B
$136M 2.29%
1,672,416
+1,478
+0.1% +$111K
ILMN icon
12
Illumina
ILMN
$28.7B
$134M 2.25%
371,908
+192,008
+107% +$61.2M
CERN
13
DELISTED
Cerner Corp
CERN
$134M 2.24%
1,701,680
+309,631
+22% +$22.9M
MASI
14
DELISTED
Masimo
MASI
$126M 2.11%
469,416
+19,026
+4% +$4.74M
GMED icon
15
Globus Medical
GMED
$10.6B
$107M 1.8%
+1,640,859
New +$94.3M
RNAM
16
DELISTED
Avidity Biosciences
RNAM
$102M 1.71%
3,995,000
TARS icon
17
Tarsus Pharmaceuticals
TARS
$2.62B
$99M 1.66%
+2,463,601
New +$70.2M
AXNX
18
DELISTED
Axonics, Inc. Common Stock
AXNX
$94M 1.58%
1,883,864
DMTK
19
DELISTED
DermTech, Inc. Common Stock
DMTK
$93.7M 1.57%
2,887,215
TXG icon
20
10x Genomics
TXG
$5.83B
$93.6M 1.57%
660,933
LONA
21
LeonaBio Inc
LONA
$69.1M
$88.9M 1.49%
268,578
+1,687
+0.6% +$398K
ESTA icon
22
Establishment Labs
ESTA
$2.71B
$87.3M 1.46%
2,319,138
KRRO icon
23
Korro Bio
KRRO
$155M
$86.8M 1.46%
49,230
ADVM
24
DELISTED
Adverum Biotechnologies
ADVM
$78.3M 1.31%
722,736
-740
-0.1% -$91.6K
GH icon
25
Guardant Health
GH
$19.3B
$75M 1.26%
581,970
+112,472
+24% +$12.9M

Similar funds

RTW Investments's Q4 2020 Portfolio in Review

As of Q4 2020, RTW Investments held 116 positions worth $5.96B, up 44% from $4.15B the previous quarter. Its ten largest holdings account for 48% of the portfolio.

RTW Investments deployed $286M of net new capital in Q4 2020, opening 25 new positions and adding to 35 existing holdings. Its largest new stake was Globus Medical: 1,640,859 shares worth $107M.

By sector, the portfolio is most concentrated in Healthcare at 94% of assets, up from 93% a quarter earlier, followed by Financials and Materials.

On the sell side, the largest reduction was OraSure Technologies, an estimated $24.8M trimmed.

  • RTW Investments's largest Q4 2020 buy was Globus Medical: 1,640,859 shares worth $107M.
  • RTW Investments added most to Illumina in Q4 2020, an estimated $61.2M increase.
  • RTW Investments's biggest Q4 2020 reduction was OraSure Technologies, cutting an estimated $24.8M.
  • RTW Investments fully exited MyoKardia, Inc. Common Stock in Q4 2020, selling an estimated $128M.
  • RTW Investments's ten largest holdings make up 48% of its $5.96B portfolio in Q4 2020.
  • RTW Investments opened 25 new positions and closed 14 in Q4 2020.
  • RTW Investments's portfolio value rose 44% quarter-over-quarter to $5.96B.

Based on RTW Investments's 13F filing for Q4 2020, filed 16 Feb 2021.