RI
RNAM

RTW Investments’s Avidity Biosciences RNAM Stock Holding History

RTW Investments’s Portfolio RNAM Stock Details RNAM Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-11,372,829
Closed -$496M – 101
2025
Q3 		$496M Buy
11,372,829
+1,753,984
+18% +$70.9M 6.11% 3
2025
Q2 		$273M Buy
9,618,845
+871,919
+10% +$26M 3.89% 9
2025
Q1 		$258M Buy
8,746,926
+814,056
+10% +$25.4M 3.95% 8
2024
Q4 		$231M Sell
7,932,870
-200,000
-2% -$8.36M 3.49% 6
2024
Q3 		$374M Sell
8,132,870
-673,968
-8% -$29.2M 5.4% 3
2024
Q2 		$360M Buy
8,806,838
+836,569
+10% +$24M 5.57% 4
2024
Q1 		$203M Buy
7,970,269
+1,280,480
+19% +$20.1M 3% 11
2023
Q4 		$60.5M Hold
6,689,789
– – 0.95% 30
2023
Q3 		$42.7M Hold
6,689,789
– – 0.9% 30
2023
Q2 		$74.2M Buy
6,689,789
+302,611
+5% +$3.8M 1.41% 23
2023
Q1 		$98M Buy
6,387,178
+781,612
+14% +$17.2M 2.04% 19
2022
Q4 		$124M Buy
5,605,566
+434,782
+8% +$6.48M 2.54% 15
2022
Q3 		$84.4M Buy
5,170,784
+375,784
+8% +$7.19M 1.95% 18
2022
Q2 		$69.7M Hold
4,795,000
– – 1.8% 18
2022
Q1 		$88.6M Hold
4,795,000
– – 1.83% 22
2021
Q4 		$114M Hold
4,795,000
– – 1.66% 19
2021
Q3 		$118M Buy
4,795,000
+800,000
+20% +$17.4M 1.78% 17
2021
Q2 		$98.7M Hold
3,995,000
– – 1.49% 23
2021
Q1 		$87.1M Hold
3,995,000
– – 1.36% 26
2020
Q4 		$102M Hold
3,995,000
– – 1.71% 16
2020
Q3 		$110M Hold
3,995,000
– – 2.65% 11
2020
Q2 		$104M Buy
+3,995,000
New +$115M 2.92% 9

Other funds holding RNAM

Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London $209B AUM 37.72% 1-Year Est. Return
Balyasny Asset Management
Balyasny Asset Management Chicago, Illinois $80.2B AUM 51.53% 1-Year Est. Return
PCM
Pentwater Capital Management Naples, Florida $16.4B AUM 55.44% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
HI
HBK Investments Dallas, Texas $10.2B AUM 67.73% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return

RTW Investments's RNAM Position: Q4 2025 in Review

RTW Investments sold out of Avidity Biosciences (RNAM) in Q4 2025, closing a stake of 11,372,829 shares — an estimated $496M sold.

RTW Investments first reported a position in RNAM in Q2 2020 and held it in 22 quarters. The position peaked at $496M in Q3 2025. 343 funds tracked by Wall St. Rank hold RNAM as of Q4 2025.

  • RTW Investments reported no remaining Avidity Biosciences position as of Q4 2025 after selling out during the quarter.
  • RTW Investments sold 11,372,829 Avidity Biosciences shares in Q4 2025, an estimated $496M.
  • RTW Investments first reported a position in Avidity Biosciences in Q2 2020 and held it in 22 quarters.
  • RTW Investments's Avidity Biosciences position peaked at $496M in Q3 2025.
  • 343 funds tracked by Wall St. Rank held Avidity Biosciences as of Q4 2025.

Based on RTW Investments's 13F filing for Q4 2025, filed 17 Feb 2026.