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RNAM

Avidity Biosciences
RNAM

Delisted

RNAM was delisted on the 26th of February, 2026.

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343 hedge funds and large institutions have $10.8B invested in Avidity Biosciences in 2025 Q4 according to their latest regulatory filings, with 157 funds opening new positions, 70 increasing their positions, 86 reducing their positions, and 81 closing their positions.

New
Increased
Maintained
Reduced
Closed

267% more funds holding in top 10

Funds holding in top 10: 9 → 33 (+24)

94% more first-time investments, than exits

New positions opened: 157 | Existing positions closed: 81

54% more capital invested

Capital invested by funds: $7.01B → $10.8B (+$3.79B)

26% more funds holding

Funds holding: 272 → 343 (+71)

10.95% less ownership

Funds ownership: 110.32% → 99.37% (-11%)

19% less repeat investments, than reductions

Existing positions increased: 70 | Existing positions reduced: 86

76% less call options, than puts

Call options by funds: $64.3M | Put options by funds: $264M

Holders
343
Holders Change
+71
Holders Change %
+26.1%
% of All Funds
4.17%
Holding in Top 10
33
Holding in Top 10 Change
+24
Holding in Top 10 Change %
+266.67%
% of All Funds
0.4%
New
157
Increased
70
Reduced
86
Closed
81
Calls
$64.3M
Puts
$264M
Net Calls
-$199M
Net Calls Change
-$237M

Top Buyers

1
Balyasny Asset Management
Balyasny Asset Management
Illinois
+$390M
2
PCM
Pentwater Capital Management
Florida
+$389M
3
HI
HBK Investments
Texas
+$282M
4
UOC
UBS O'Connor
Illinois
+$240M
5
BlackRock
BlackRock
New York
+$236M

Top Sellers

1
Fidelity Investments
Fidelity Investments
Massachusetts
-$1.38B
2
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$623M
3
Wellington Management Group
Wellington Management Group
Massachusetts
-$603M
4
RI
RTW Investments
New York
-$496M
5
Janus Henderson Group
Janus Henderson Group
United Kingdom
-$490M
Name Holding Trade Value Shares
Change 		Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$985M +$27.7M +429,491 +3%
BlackRock
2
BlackRock
New York
$927M +$236M +3,648,222 +40%
RCM
3
RA Capital Management
Massachusetts
$623M – – –
Janus Henderson Group
4
Janus Henderson Group
United Kingdom
$501M -$490M -7,583,412 -52%
Balyasny Asset Management
5
Balyasny Asset Management
Illinois
$436M +$390M +6,040,590 New
PCM
6
Pentwater Capital Management
Florida
$435M +$389M +6,026,500 New
ACA
7
Avoro Capital Advisors
New York
$393M -$141M -2,190,000 -29%
HI
8
HBK Investments
Texas
$315M +$282M +4,365,000 New
State Street
9
State Street
Massachusetts
$296M -$51.1M -790,747 -16%
Goldman Sachs
10
Goldman Sachs
New York
$272M +$132M +2,044,316 +118%
UOC
11
UBS O'Connor
Illinois
$268M +$240M +3,716,597 New
FCM
12
Farallon Capital Management
California
$233M +$209M +3,233,000 New
Geode Capital Management
13
Geode Capital Management
Massachusetts
$225M +$17M +262,731 +9%
Norges Bank
14
Norges Bank
Norway
$220M +$197M +3,046,388 New
BG
15
Bellevue Group
Switzerland
$190M +$30.9M +478,107 +22%
Adage Capital Partners
16
Adage Capital Partners
Massachusetts
$190M +$92.4M +1,430,966 +119%
GCL
17
Glazer Capital LLC
New York
$178M +$159M +2,467,139 New
UBS Group
18
UBS Group
Switzerland
$170M +$67.2M +1,040,953 +79%
WAM
19
Weiss Asset Management
Massachusetts
$156M +$140M +2,161,093 New
Millennium Management
20
Millennium Management
New York
$156M +$137M +2,127,647 +7,182%
TAL
21
TIG Advisors LLC
New York
$130M +$116M +1,801,683 New
Citadel Advisors
22
Citadel Advisors
Florida
$115M +$44.7M +692,665 +77%
Charles Schwab
23
Charles Schwab
California
$85.2M +$3.74M +57,884 +5%
MF
24
Magnetar Financial
Illinois
$83.6M +$74.8M +1,158,603 New
Fidelity International
25
Fidelity International
Bermuda
$82.5M +$73.9M +1,144,000 New
1
2 3 4 5

RNAM Hedge Fund Activity: Q4 2025 in Review

343 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Avidity Biosciences (RNAM) for Q4 2025, worth a combined $10.8B — up 54% from $7.01B a quarter earlier.

Buyers outnumbered sellers: 157 funds opened new RNAM positions and 81 closed out — a net gain of 76 holders — while 70 added to existing stakes and 86 trimmed.

The largest buyer was Balyasny Asset Management, opening a new position worth an estimated $390M. The largest seller was Fidelity Investments, cutting an estimated $1.38B.

  • 343 institutional investors held Avidity Biosciences (RNAM) as of Q4 2025, up from 272 in Q3 2025.
  • Funds reported $10.8B of Avidity Biosciences stock for Q4 2025, up 54% quarter-over-quarter.
  • 157 funds opened new Avidity Biosciences positions in Q4 2025 and 81 closed out, a net change of +76 holders.
  • The largest Avidity Biosciences buyer in Q4 2025 was Balyasny Asset Management, an estimated $390M added.
  • The largest Avidity Biosciences seller in Q4 2025 was Fidelity Investments, an estimated $1.38B sold.

Based on aggregated 13F filings for Q4 2025.