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RNAM

Avidity Biosciences

Delisted

RNAM was delisted on the 26th of February, 2026.

220 hedge funds and large institutions have $3.99B invested in Avidity Biosciences in 2025 Q1 according to their latest regulatory filings, with 30 funds opening new positions, 98 increasing their positions, 65 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

51% more repeat investments, than reductions

Existing positions increased: 98 | Existing positions reduced: 65

13% more funds holding in top 10

Funds holding in top 10: 89 (+1)

7% more capital invested

Capital invested by funds: $3.71B → $3.99B (+$274M)

4.7% more ownership

Funds ownership: 106.99%111.68% (+4.7%)

7% less funds holding

Funds holding: 236220 (-16)

32% less first-time investments, than exits

New positions opened: 30 | Existing positions closed: 44

70% less call options, than puts

Call options by funds: $9.04M | Put options by funds: $30.3M

Holders
220
Holders Change
-16
Holders Change %
-6.78%
% of All Funds
2.95%
Holding in Top 10
9
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+12.5%
% of All Funds
0.12%
New
30
Increased
98
Reduced
65
Closed
44
Calls
$9.04M
Puts
$30.3M
Net Calls
-$21.3M
Net Calls Change
-$19.9M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$461M -$27.9M -894,542 -5%
Janus Henderson Group
2
Janus Henderson Group
United Kingdom
$361M +$136M +4,373,686 +62%
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$335M +$9.2M +295,275 +3%
BlackRock
4
BlackRock
New York
$293M -$464K -14,895 -0.1%
Wellington Management Group
5
Wellington Management Group
Massachusetts
$286M +$49.2M +1,578,459 +19%
Vanguard Group
6
Vanguard Group
Pennsylvania
$273M -$5.88M -188,706 -2%
RI
7
RTW Investments
New York
$258M +$25.4M +814,056 +10%
ACA
8
Avoro Capital Advisors
New York
$225M +$3.89M +125,000 +2%
RCM
9
RA Capital Management
Massachusetts
$186M
State Street
10
State Street
Massachusetts
$128M -$8.75M -280,831 -6%
Geode Capital Management
11
Geode Capital Management
Massachusetts
$81.4M -$1.63M -52,209 -2%
Adage Capital Partners
12
Adage Capital Partners
Massachusetts
$63.3M -$18.9M -606,063 -22%
CC
13
Casdin Capital
New York
$60.4M
O
14
OrbiMed
New York
$53.5M +$21.8M +700,000 +63%
PCH
15
Polar Capital Holdings
United Kingdom
$52.8M +$16.1M +516,977 +41%
Bank of America
16
Bank of America
North Carolina
$46.5M +$43.5M +1,395,900 +782%
DCM
17
Driehaus Capital Management
Illinois
$37.5M +$1.34M +42,873 +3%
SL
18
Siren LLC
Connecticut
$32.8M -$520K -16,685 -1%
Charles Schwab
19
Charles Schwab
California
$30.2M -$167K -5,353 -0.5%
Northern Trust
20
Northern Trust
Illinois
$30.1M -$1.9M -60,952 -6%
Artisan Partners
21
Artisan Partners
Wisconsin
$27.4M -$2.71M -87,024 -9%
Pictet Asset Management
22
Pictet Asset Management
Switzerland
$25.8M +$2.31M +74,194 +9%
WP
23
Woodline Partners
California
$25.6M +$3.27K +105 +0%
BCM
24
Boxer Capital Management
California
$25.5M -$26.9M -862,388 -50%
Norges Bank
25
Norges Bank
Norway
$24.7M +$3.53M +113,431 +16%

RNAM Hedge Fund Activity: Q1 2025 in Review

220 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Avidity Biosciences (RNAM) for Q1 2025, worth a combined $3.99B — up 7.4% from $3.71B a quarter earlier.

Sellers outnumbered buyers: 44 funds closed out of RNAM and 30 opened new positions — a net loss of 14 holders — while 65 trimmed existing stakes and 98 added.

The largest buyer was Janus Henderson Group, adding an estimated $136M. The largest seller was Fidelity Investments, cutting an estimated $27.9M.

  • 220 institutional investors held Avidity Biosciences (RNAM) as of Q1 2025, down from 236 in Q4 2024.
  • Funds reported $3.99B of Avidity Biosciences stock for Q1 2025, up 7.4% quarter-over-quarter.
  • 30 funds opened new Avidity Biosciences positions in Q1 2025 and 44 closed out, a net change of -14 holders.
  • The largest Avidity Biosciences buyer in Q1 2025 was Janus Henderson Group, an estimated $136M added.
  • The largest Avidity Biosciences seller in Q1 2025 was Fidelity Investments, an estimated $27.9M sold.

Based on aggregated 13F filings for Q1 2025.