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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
+33.59%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$380M
AUM Growth
+$114M
Cap. Flow
+$37.3M
Cap. Flow %
9.82%
Top 10 Hldgs %
77.18%
Holding
35
New
3
Increased
16
Reduced
6
Closed
7

Top Buys

1
RGNX icon
Regenxbio
RGNX
+$18.8M
2
ALNY icon
Alnylam Pharmaceuticals
ALNY
+$14M
3
MDCO
Medicines Co
MDCO
+$9.05M
4
ATRA icon
Atara Biotherapeutics
ATRA
+$8.88M
5
OSUR icon
OraSure Technologies
OSUR
+$5.86M

Top Sells

1
AVXS
AveXis, Inc. Common Stock
AVXS
+$14M
2
USO icon
United States Oil Fund
USO
+$7.91M
3
BCRX icon
BioCryst Pharmaceuticals
BCRX
+$4.32M
4
OMER icon
Omeros
OMER
+$2.57M
5
BLUE
bluebird bio
BLUE
+$1.49M

Sector Composition

1 Healthcare 89.59%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ALNY icon
1
Alnylam Pharmaceuticals
ALNY
$37.8B
$56M 14.74%
1,092,516
+303,308
+38% +$14M
AVXS
2
DELISTED
AveXis, Inc. Common Stock
AVXS
$47.4M 12.47%
623,330
-225,713
-27% -$14M
BMY icon
3
Bristol-Myers Squibb
BMY
$124B
$31M 8.17%
570,692
+4,804
+0.8% +$263K
LJPC
4
DELISTED
La Jolla Pharmaceutical Company
LJPC
$30.7M 8.08%
1,028,929
-57,108
-5% -$1.46M
BCRX icon
5
BioCryst Pharmaceuticals
BCRX
$2.32B
$29M 7.65%
3,458,120
-620,775
-15% -$4.32M
MDCO
6
DELISTED
Medicines Co
MDCO
$28M 7.37%
572,689
+198,426
+53% +$9.05M
RGNX icon
7
Regenxbio
RGNX
$579M
$23.5M 6.18%
1,216,505
+976,716
+407% +$18.8M
ATRA icon
8
Atara Biotherapeutics
ATRA
$78.6M
$18.7M 4.92%
36,349
+21,444
+144% +$8.88M
AGEN
9
Agenus
AGEN
$208M
$16M 4.21%
216,328
+1,815
+0.8% +$144K
PTCT icon
10
PTC Therapeutics
PTCT
$6.51B
$12.8M 3.38%
1,305,643
+308,477
+31% +$3.73M
INCY icon
11
Incyte
INCY
$23.3B
$11M 2.9%
82,490
-4,267
-5% -$543K
OXFD
12
DELISTED
Oxford Immunotec Global PLC Ordinary Shares
OXFD
$9.49M 2.5%
612,903
+69,616
+13% +$994K
BLUE
13
DELISTED
bluebird bio
BLUE
$9.42M 2.48%
7,999
-1,464
-15% -$1.49M
MASI
14
DELISTED
Masimo
MASI
$7.54M 1.99%
80,900
– –
OSUR icon
15
OraSure Technologies
OSUR
$273M
$7.32M 1.93%
+566,230
New +$5.86M
VIVE
16
DELISTED
VIVEVE MED INC
VIVE
$7.25M 1.91%
1,146
+306
+36% +$1.49M
DRNA
17
DELISTED
Dicerna Pharmaceuticals, Inc.
DRNA
$7.01M 1.85%
2,062,991
+19,775
+1% +$55.7K
CORI
18
DELISTED
Corium International, Inc.
CORI
$6.06M 1.59%
1,448,991
+347,946
+32% +$1.28M
TCMD icon
19
Tactile Systems Technology
TCMD
$663M
$5.46M 1.44%
287,876
+39,114
+16% +$665K
ABUS icon
20
Arbutus Biopharma
ABUS
$936M
$4.7M 1.24%
+1,446,587
New +$4.01M
VRAY
21
DELISTED
ViewRay, Inc.
VRAY
$4.39M 1.16%
+515,612
New +$2.81M
IVTY
22
DELISTED
Invuity, Inc
IVTY
$3.74M 0.98%
470,167
+15,267
+3% +$111K
GBT
23
DELISTED
Global Blood Therapeutics, Inc.
GBT
$965K 0.25%
26,183
+220
+0.8% +$5.54K
CLDX icon
24
Celldex Therapeutics
CLDX
$2.78B
$873K 0.23%
16,113
+136
+0.9% +$7.08K
TMBR
25
DELISTED
Timber Pharmaceuticals, Inc.
TMBR
$648K 0.17%
86
+1
+1% +$6.92K
1
2

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BEI
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MG
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LWCFA
Loring Wolcott & Coolidge Fiduciary Advisors Boston, Massachusetts $9.98B AUM 4.97% 1-Year Est. Return
HRCM
Hood River Capital Management Palm Beach Gardens, Florida $9.98B AUM 145.42% 1-Year Est. Return
RA
Royce & Associates New York $10.1B AUM 42.88% 1-Year Est. Return
OAM
OP Asset Management Helsinki $9.95B AUM 30.22% 1-Year Est. Return
GI
GAMCO Investors Greenwich, Connecticut $10.2B AUM 30.27% 1-Year Est. Return
IIM
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RTW Investments's Q1 2017 Portfolio in Review

As of Q1 2017, RTW Investments held 35 positions worth $380M, up 43% from $266M the previous quarter. Its ten largest holdings account for 77% of the portfolio.

RTW Investments deployed $37.3M of net new capital in Q1 2017, opening 3 new positions and adding to 16 existing holdings. Its largest new stake was OraSure Technologies: 566,230 shares worth $7.32M.

By sector, the portfolio is most concentrated in Healthcare at 90% of assets, down from 90% a quarter earlier.

On the sell side, the largest reduction was AveXis, Inc. Common Stock, an estimated $14M trimmed.

  • RTW Investments's largest Q1 2017 buy was OraSure Technologies: 566,230 shares worth $7.32M.
  • RTW Investments added most to Regenxbio in Q1 2017, an estimated $18.8M increase.
  • RTW Investments's biggest Q1 2017 reduction was AveXis, Inc. Common Stock, cutting an estimated $14M.
  • RTW Investments fully exited United States Oil Fund in Q1 2017, selling an estimated $7.91M.
  • RTW Investments's ten largest holdings make up 77% of its $380M portfolio in Q1 2017.
  • RTW Investments opened 3 new positions and closed 7 in Q1 2017.
  • RTW Investments's portfolio value rose 43% quarter-over-quarter to $380M.

Based on RTW Investments's 13F filing for Q1 2017, filed 15 May 2017.