RTW Investments’s Tango Therapeutics TNGX Stock Holding History

RTW Investments’s Portfolio TNGX Stock Details TNGX Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$278M	Buy	13,300,620 +11,809,392	+792%	+$164M	2.77%	8
2025 Q4	$13.2M	Buy	+1,491,228	New	+$12.8M	0.13%	67
2024 Q1	–	Sell	-1,966,752	Closed	-$19.5M	–	77
2023 Q4	$19.5M	Buy	+1,966,752	New	+$17.1M	0.3%	43
2022 Q1	–	Sell	-180,819	Closed	-$1.98M	–	120
2021 Q4	$1.98M	Sell	180,819 -419,181	-70%	-$5.04M	0.03%	109
2021 Q3	$7.76M	Hold	600,000	–	–	0.12%	82
2021 Q2	$6.83M	Hold	600,000	–	–	0.1%	82
2021 Q1	$6.67M	Hold	600,000	–	–	0.1%	83
2020 Q4	$6.86M	Hold	600,000	–	–	0.12%	77
2020 Q3	$6.22M	Buy	+600,000	New	+$6.13M	0.15%	75

Other funds holding TNGX

Adage Capital Partners Boston, Massachusetts $64.8B AUM 42.7% 1-Year Est. Return

BCM

Boxer Capital Management San Diego, California $762M AUM 1,125.36% 1-Year Est. Return

TCM

TCG Crossover Management Palo Alto, California $3.5B AUM 1,165.83% 1-Year Est. Return

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

FCM

Farallon Capital Management San Francisco, California $17.5B AUM 50.95% 1-Year Est. Return

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

Woodline Partners San Francisco, California $26.4B AUM 44.85% 1-Year Est. Return

Nextech Invest Zurich, Switzerland $1.42B AUM 304.47% 1-Year Est. Return

TGI

TRV GP IV Boston, Massachusetts $267M AUM 965.83% 1-Year Est. Return

Siren LLC Greenwich, Connecticut $3.61B AUM 203.3% 1-Year Est. Return

RTW Investments's TNGX Position: Q1 2026 in Review

RTW Investments increased its Tango Therapeutics (TNGX) stake by 792% in Q1 2026, buying an estimated $164M and bringing the position to 13,300,620 shares worth $278M. The position accounts for 2.77% of the portfolio, ranked #8.

RTW Investments first reported a position in TNGX in Q3 2020 and has held it in 9 quarters since. 194 funds tracked by Wall St. Rank hold TNGX as of Q1 2026.

RTW Investments held 13,300,620 shares of Tango Therapeutics worth $278M as of Q1 2026.
RTW Investments bought 11,809,392 Tango Therapeutics shares in Q1 2026, an estimated $164M.
Tango Therapeutics made up 2.77% of RTW Investments's portfolio in Q1 2026, its #8 holding.
RTW Investments first reported a position in Tango Therapeutics in Q3 2020 and has held it in 9 quarters since.
194 funds tracked by Wall St. Rank held Tango Therapeutics as of Q1 2026.

Based on RTW Investments's 13F filing for Q1 2026, filed 15 May 2026.