RTW Investments’s Arrowhead Research ARWR Stock Holding History

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$36.7M	Buy	585,682 +966	+0.2%	+$61.1K	0.37%	48
2025 Q4	$38.8M	Buy	+584,716	New	+$28.7M	0.39%	53
2022 Q1	–	Sell	-346,842	Closed	-$23M	–	108
2021 Q4	$23M	Buy	+346,842	New	+$23.8M	0.34%	65
2019 Q3	–	Sell	-1,120,346	Closed	-$29.7M	–	61
2019 Q2	$29.7M	Sell	1,120,346 -407,867	-27%	-$8.95M	1.59%	21
2019 Q1	$28M	Sell	1,528,213 -3,787,943	-71%	-$62.5M	1.91%	18
2018 Q4	$66M	Sell	5,316,156 -2,288,069	-30%	-$31.3M	6.06%	2
2018 Q3	$146M	Sell	7,604,225 -695,317	-8%	-$11.4M	8.73%	3
2018 Q2	$113M	Buy	8,299,542 +5,382,981	+185%	+$50.3M	8.14%	5
2018 Q1	$21M	Buy	+2,916,561	New	+$18M	2%	15
2016 Q4	–	Sell	-1,116,777	Closed	-$8.21M	–	34
2016 Q3	$8.21M	Buy	+1,116,777	New	+$7.24M	2.48%	12
2015 Q4	–	Sell	-2,097,185	Closed	-$12.1M	–	39
2015 Q3	$12.1M	Sell	2,097,185 -462,815	-18%	-$2.91M	3.75%	10
2015 Q2	$18.3M	Buy	2,560,000 +150,000	+6%	+$1.03M	5.33%	7
2015 Q1	$16.3M	Sell	2,410,000 -200,000	-8%	-$1.42M	7.36%	7
2014 Q4	$19.3M	Buy	+2,610,000	New	+$17.8M	7.13%	7