FLSM

Frazier Life Sciences Management Portfolio holdings

AUM $3.72B
1-Year Est. Return 129.71%
This Fund
S&P 500
This Quarter Est. Return
1 Year Est. Return
+129.71%
3 Year Est. Return
5 Year Est. Return
10 Year Est. Return
AUM
$3.72B
AUM Growth
+$386M
Cap. Flow
Cap. Flow %
Top 10 Hldgs %
Holding
52
New
Increased
Reduced
Closed

Top Buys

1
+$47.4M
2
+$30.5M
3
+$23.3M
4
RNAM
Avidity Biosciences
RNAM
+$23.1M
5
ACAD icon
Acadia Pharmaceuticals
ACAD
+$16.3M

Top Sells

1
+$361M
2
+$42.1M
3
+$32.8M
4
RARE icon
Ultragenyx Pharmaceutical
RARE
+$29.6M
5
BBIO icon
BridgeBio Pharma
BBIO
+$19.7M

Sector Composition

1 Healthcare 99.69%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
NAMS icon
1
NewAmsterdam Pharma
NAMS
$4.02B
$594M 15.96%
16,943,774
+241,818
MIRM icon
2
Mirum Pharmaceuticals
MIRM
$5.49B
$537M 14.42%
6,795,121
ARQT icon
3
Arcutis Biotherapeutics
ARQT
$3.18B
$287M 7.7%
9,874,511
BBIO icon
4
BridgeBio Pharma
BBIO
$12.6B
$271M 7.28%
3,545,557
-299,900
MBX
5
MBX Biosciences
MBX
$1.47B
$210M 5.64%
6,652,013
PHAT icon
6
Phathom Pharmaceuticals
PHAT
$942M
$207M 5.55%
12,466,489
MAZE
7
Maze Therapeutics
MAZE
$2.16B
$189M 5.08%
4,567,274
TRVI icon
8
Trevi Therapeutics
TRVI
$1.55B
$128M 3.45%
10,259,409
KRYS icon
9
Krystal Biotech
KRYS
$7.82B
$120M 3.23%
488,460
-200,000
IRON icon
10
Disc Medicine
IRON
$2.47B
$100M 2.69%
1,260,000
-178,534
ERAS icon
11
Erasca
ERAS
$4.26B
$84.6M 2.27%
22,729,436
KALV icon
12
KalVista Pharmaceuticals
KALV
$813M
$81.4M 2.19%
5,039,867
PVLA
13
Palvella Therapeutics
PVLA
$1.67B
$75.6M 2.03%
722,400
RNAM
14
Avidity Biosciences
RNAM
$11.2B
$70.9M 1.9%
983,125
+358,125
RVMD icon
15
Revolution Medicines
RVMD
$19.6B
$63.5M 1.71%
797,455
-200,000
DYN icon
16
Dyne Therapeutics
DYN
$2.47B
$61.7M 1.66%
3,153,082
+434,977
TARS icon
17
Tarsus Pharmaceuticals
TARS
$3.16B
$59.7M 1.6%
728,644
-438,883
SVRA icon
18
Savara
SVRA
$1.22B
$59.5M 1.6%
9,862,301
-1,600,000
CYTK icon
19
Cytokinetics
CYTK
$7.6B
$59.4M 1.6%
934,642
+44,197
ABVX
20
Abivax
ABVX
$9.25B
$51M 1.37%
378,300
LXEO icon
21
Lexeo Therapeutics
LXEO
$510M
$43.9M 1.18%
4,424,725
AGIO icon
22
Agios Pharmaceuticals
AGIO
$1.75B
$34.8M 0.94%
1,279,754
ACAD icon
23
Acadia Pharmaceuticals
ACAD
$4.07B
$34.6M 0.93%
1,297,198
+683,361
ZLAB icon
24
Zai Lab
ZLAB
$1.98B
$33.6M 0.9%
1,902,320
+275,000
RAPT icon
25
RAPT Therapeutics
RAPT
$1.68B
$33.3M 0.89%
+983,333
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