FLSM

Frazier Life Sciences Management Portfolio holdings

AUM $3.89B
1-Year Est. Return 201.1%
This Fund
S&P 500
This Quarter Est. Return
1 Year Est. Return
+201.1%
3 Year Est. Return
5 Year Est. Return
10 Year Est. Return
AUM
$3.89B
AUM Growth
+$163M
Cap. Flow
Cap. Flow %
Top 10 Hldgs %
Holding
43
New
Increased
Reduced
Closed

Top Buys

1
+$83.2M
2
+$31.1M
3
+$23M
4
GLUE icon
Monte Rosa Therapeutics
GLUE
+$19.1M
5
PVLA
Palvella Therapeutics
PVLA
+$16.7M

Top Sells

1
+$70.9M
2
+$51M
3
+$33.3M
4
RVMD icon
Revolution Medicines
RVMD
+$12.3M
5
TVTX icon
Travere Therapeutics
TVTX
+$9.23M

Sector Composition

1 Healthcare 99.74%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
MIRM icon
1
Mirum Pharmaceuticals
MIRM
$6.19B
$709M 18.25%
7,679,684
+884,563
NAMS icon
2
NewAmsterdam Pharma
NAMS
$3.94B
$542M 13.96%
16,943,774
ERAS icon
3
Erasca
ERAS
$3.99B
$399M 10.27%
24,675,188
+1,945,752
BBIO icon
4
BridgeBio Pharma
BBIO
$13B
$256M 6.59%
3,448,139
-97,418
ARQT icon
5
Arcutis Biotherapeutics
ARQT
$2.68B
$233M 5.99%
9,874,511
MBX
6
MBX Biosciences
MBX
$1.5B
$199M 5.11%
6,652,013
PHAT icon
7
Phathom Pharmaceuticals
PHAT
$765M
$139M 3.56%
12,466,489
MAZE
8
Maze Therapeutics
MAZE
$1.46B
$136M 3.51%
4,567,274
KRYS icon
9
Krystal Biotech
KRYS
$9.11B
$124M 3.2%
481,307
-7,153
TRVI icon
10
Trevi Therapeutics
TRVI
$2.01B
$119M 3.05%
9,939,547
-319,862
PVLA
11
Palvella Therapeutics
PVLA
$1.7B
$110M 2.83%
882,400
+160,000
KALV icon
12
KalVista Pharmaceuticals
KALV
$1.43B
$99.9M 2.57%
4,961,108
-78,759
IRON icon
13
Disc Medicine
IRON
$2.66B
$86.6M 2.23%
1,354,852
+94,852
CYTK icon
14
Cytokinetics
CYTK
$10.4B
$76.4M 1.97%
1,159,879
+225,237
RVMD icon
15
Revolution Medicines
RVMD
$33.5B
$65.7M 1.69%
675,686
-121,769
DYN icon
16
Dyne Therapeutics
DYN
$3.2B
$57.2M 1.47%
3,153,082
SVRA icon
17
Savara
SVRA
$1.07B
$53.1M 1.37%
9,720,852
-141,449
TARS icon
18
Tarsus Pharmaceuticals
TARS
$2.56B
$51.1M 1.32%
728,644
VOR icon
19
Vor Biopharma
VOR
$811M
$45.4M 1.17%
2,543,939
AGIO icon
20
Agios Pharmaceuticals
AGIO
$1.75B
$42.5M 1.09%
1,256,080
-23,674
BCRX icon
21
BioCryst Pharmaceuticals
BCRX
$2.26B
$38.2M 0.98%
+4,009,240
ZLAB icon
22
Zai Lab
ZLAB
$1.99B
$35.8M 0.92%
1,902,320
AURA icon
23
Aura Biosciences
AURA
$772M
$34.1M 0.88%
5,100,000
ACAD icon
24
Acadia Pharmaceuticals
ACAD
$3.71B
$32M 0.82%
1,438,198
+141,000
ASND icon
25
Ascendis Pharma A/S
ASND
$13.8B
$30.5M 0.78%
133,333
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