FLSM

Frazier Life Sciences Management Portfolio holdings

AUM $3.72B
1-Year Est. Return 129.71%
This Fund
S&P 500
This Quarter Est. Return
1 Year Est. Return
+129.71%
3 Year Est. Return
5 Year Est. Return
10 Year Est. Return
AUM
$3.34B
AUM Growth
+$837M
Cap. Flow
Cap. Flow %
Top 10 Hldgs %
Holding
53
New
Increased
Reduced
Closed

Top Buys

1
+$23.2M
2
+$14.5M
3
+$13.8M
4
DYN icon
Dyne Therapeutics
DYN
+$13.8M
5
ZLAB icon
Zai Lab
ZLAB
+$11M

Top Sells

1
+$21.1M
2
+$20M
3
+$12.9M
4
COGT icon
Cogent Biosciences
COGT
+$12.5M
5
TVTX icon
Travere Therapeutics
TVTX
+$11.5M

Sector Composition

1 Healthcare 99.74%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
MIRM icon
1
Mirum Pharmaceuticals
MIRM
$5.4B
$498M 14.93%
6,795,121
NAMS icon
2
NewAmsterdam Pharma
NAMS
$3.84B
$475M 14.23%
16,701,956
+94,882
VRNA
3
DELISTED
Verona Pharma
VRNA
$361M 10.82%
3,383,950
BBIO icon
4
BridgeBio Pharma
BBIO
$12.4B
$200M 5.98%
3,845,457
+45,000
ARQT icon
5
Arcutis Biotherapeutics
ARQT
$3.11B
$186M 5.58%
9,874,511
PHAT icon
6
Phathom Pharmaceuticals
PHAT
$921M
$147M 4.4%
12,466,489
KRYS icon
7
Krystal Biotech
KRYS
$7.83B
$122M 3.64%
688,460
MAZE
8
Maze Therapeutics
MAZE
$2.17B
$118M 3.55%
4,567,274
-1
MBX
9
MBX Biosciences
MBX
$1.48B
$116M 3.49%
6,652,013
+666,666
IRON icon
10
Disc Medicine
IRON
$2.5B
$95.1M 2.85%
1,438,534
-216,300
TRVI icon
11
Trevi Therapeutics
TRVI
$1.61B
$93.9M 2.81%
10,259,409
TARS icon
12
Tarsus Pharmaceuticals
TARS
$3.21B
$69.4M 2.08%
1,167,527
-230,000
KALV icon
13
KalVista Pharmaceuticals
KALV
$831M
$61.4M 1.84%
5,039,867
+152,000
ZLAB icon
14
Zai Lab
ZLAB
$2.05B
$55.1M 1.65%
1,627,320
+319,182
AGIO icon
15
Agios Pharmaceuticals
AGIO
$1.69B
$51.4M 1.54%
1,279,754
ERAS icon
16
Erasca
ERAS
$4.29B
$49.6M 1.48%
22,729,436
CYTK icon
17
Cytokinetics
CYTK
$7.48B
$48.9M 1.47%
890,445
+335,714
RVMD icon
18
Revolution Medicines
RVMD
$19.7B
$46.6M 1.4%
997,455
PVLA
19
Palvella Therapeutics
PVLA
$1.59B
$45.3M 1.36%
722,400
SVRA icon
20
Savara
SVRA
$1.24B
$40.9M 1.23%
11,462,301
DYN icon
21
Dyne Therapeutics
DYN
$2.48B
$34.4M 1.03%
2,718,105
+1,212,121
ABVX
22
Abivax
ABVX
$9.18B
$32.1M 0.96%
+378,300
AURA icon
23
Aura Biosciences
AURA
$380M
$31.5M 0.94%
5,100,000
RARE icon
24
Ultragenyx Pharmaceutical
RARE
$2.22B
$29.6M 0.89%
983,715
LXEO icon
25
Lexeo Therapeutics
LXEO
$515M
$29.4M 0.88%
4,424,725
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