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FLSM
Frazier Life Sciences Management Portfolio holdings
AUM
$3.89B
1-Year Est. Return
201.1%
This Fund
S&P 500
This Quarter
Est. Return
+10.82%
1 Year Est. Return
+201.1%
3 Year Est. Return
+879.31%
5 Year Est. Return
–
10 Year Est. Return
–
AUM
$2.5B
AUM Growth
+$313M
(+14%)
Cap. Flow
+$193M
Cap. Flow
% of AUM
7.73%
Top 10 Holdings %
Top 10 Hldgs %
67.82%
Holding
55
New
8
Increased
16
Reduced
5
Closed
6
Top Buys
| 1 |
JBIO
Jade Biosciences
JBIO
|
+$60.3M |
| 2 |
Zai Lab
ZLAB
|
+$31.5M |
| 3 |
Aura Biosciences
AURA
|
+$29.8M |
| 4 |
Evolus
EOLS
|
+$24.9M |
| 5 |
Cytokinetics
CYTK
|
+$19.3M |
Top Sells
| 1 |
Rhythm Pharmaceuticals
RYTM
|
+$36M |
| 2 |
SLNO
Soleno Therapeutics
SLNO
|
+$35.7M |
| 3 |
MRUS
Merus
MRUS
|
+$15.7M |
| 4 |
Acadia Pharmaceuticals
ACAD
|
+$7.81M |
| 5 |
Rocket Pharmaceuticals
RCKT
|
+$7.2M |
Sector Composition
| 1 | Healthcare | 99.84% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
1
Mirum Pharmaceuticals
MIRM
$7.18B
| $346M | 13.83% |
6,795,121
| – | – |
|
|
VRNA
2
DELISTED
Verona Pharma
VRNA
| $320M | 12.8% |
3,383,950
-73,900
| -2% | -$5.47M |
|
3
NewAmsterdam Pharma
NAMS
$3.7B
| $301M | 12.03% |
16,607,074
+490,656
| +3% | +$8.95M |
|
4
BridgeBio Pharma
BBIO
$16B
| $164M | 6.56% |
3,800,457
| – | – |
|
5
Arcutis Biotherapeutics
ARQT
$3.46B
| $138M | 5.54% |
9,874,511
+1,089,227
| +12% | +$15.3M |
|
6
Phathom Pharmaceuticals
PHAT
$878M
| $120M | 4.78% |
12,466,489
+2,357,210
| +23% | +$13M |
|
7
Krystal Biotech
KRYS
$10.2B
| $94.6M | 3.78% |
688,460
| – | – |
|
8
Disc Medicine
IRON
$2.81B
| $87.6M | 3.5% |
1,654,834
-100,000
| -6% | -$4.7M |
|
|
MBX
9
MBX Biosciences
MBX
$2.81B
| $68.3M | 2.73% |
5,985,347
| – | – |
|
10
Tarsus Pharmaceuticals
TARS
$2.57B
| $56.6M | 2.26% |
1,397,527
| – | – |
|
11
Trevi Therapeutics
TRVI
$2.46B
| $56.1M | 2.24% |
10,259,409
| – | – |
|
|
MAZE
12
Maze Therapeutics
MAZE
$1.53B
| $56M | 2.24% |
4,567,275
+438,274
| +11% | +$4.56M |
|
|
KALV
13
DELISTED
KalVista Pharmaceuticals
KALV
| $55.3M | 2.21% |
4,887,867
| – | – |
|
|
14
Zai Lab
ZLAB
$2.34B
| $45.7M | 1.83% |
1,308,138
+958,138
| +274% | +$31.5M |
|
15
Agios Pharmaceuticals
AGIO
$2.31B
| $42.6M | 1.7% |
1,279,754
+209,900
| +20% | +$6.36M |
|
16
Revolution Medicines
RVMD
$37.9B
| $36.7M | 1.47% |
997,455
| – | – |
|
17
Ultragenyx Pharmaceutical
RARE
$2.97B
| $35.8M | 1.43% |
983,715
+325,000
| +49% | +$11.7M |
|
|
18
Aura Biosciences
AURA
$698M
| $31.9M | 1.28% |
+5,100,000
| New | +$29.8M |
|
19
Erasca
ERAS
$6.01B
| $28.9M | 1.15% |
22,729,436
+153,585
| +0.7% | +$206K |
|
20
Alkermes
ALKS
$8.86B
| $28.6M | 1.14% |
1,000,647
+399,518
| +66% | +$11.9M |
|
21
Savara
SVRA
$1.15B
| $26.1M | 1.05% |
11,462,301
| – | – |
|
|
MREO
22
Mereo BioPharma
MREO
$52.1M
| $25.6M | 1.02% |
9,440,112
+1,620,249
| +21% | +$3.91M |
|
23
Ascendis Pharma A/S
ASND
$17.2B
| $23M | 0.92% |
133,333
| – | – |
|
|
24
Evolus
EOLS
$377M
| $22.4M | 0.9% |
+2,435,550
| New | +$24.9M |
|
|
HLVX
25
DELISTED
HilleVax
HLVX
| $21.1M | 0.84% |
10,617,062
| – | – |
|
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