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FLSM
Frazier Life Sciences Management Portfolio holdings
AUM
$3.89B
1-Year Est. Return
201.1%
This Fund
S&P 500
This Quarter
Est. Return
+5.39%
1 Year Est. Return
+201.1%
3 Year Est. Return
+879.31%
5 Year Est. Return
–
10 Year Est. Return
–
AUM
$1.51B
AUM Growth
-$169M
(-10%)
Cap. Flow
-$38.2M
Cap. Flow
% of AUM
-2.54%
Top 10 Holdings %
Top 10 Hldgs %
63.08%
Holding
56
New
8
Increased
10
Reduced
5
Closed
4
Top Buys
| 1 |
Mirum Pharmaceuticals
MIRM
|
+$57.8M |
| 2 |
APLS
Apellis Pharmaceuticals
APLS
|
+$27M |
| 3 |
Rocket Pharmaceuticals
RCKT
|
+$25.5M |
| 4 |
BridgeBio Pharma
BBIO
|
+$20.9M |
| 5 |
AN2 Therapeutics
ANTX
|
+$15.7M |
Top Sells
| 1 |
KDNY
Chinook Therapeutics, Inc. Common Stock
KDNY
|
+$167M |
| 2 |
Syndax Pharmaceuticals
SNDX
|
+$58.8M |
| 3 |
MORF
Morphic Holding, Inc. Common Stock
MORF
|
+$15.2M |
| 4 |
RETA
Reata Pharmaceuticals, Inc. Class A Common Stock
RETA
|
+$10.2M |
| 5 |
Acadia Pharmaceuticals
ACAD
|
+$6.15M |
Sector Composition
| 1 | Healthcare | 99.83% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
|
1
Mirum Pharmaceuticals
MIRM
$7.19B
| $204M | 13.58% |
6,470,392
+2,110,285
| +48% | +$57.8M |
|
|
HLVX
2
DELISTED
HilleVax
HLVX
| $132M | 8.74% |
9,781,472
| – | – |
|
3
Krystal Biotech
KRYS
$10.2B
| $115M | 7.62% |
988,460
-1,800
| -0.2% | -$220K |
|
4
NewAmsterdam Pharma
NAMS
$3.7B
| $112M | 7.45% |
12,131,705
+1,259,902
| +12% | +$13.6M |
|
5
Phathom Pharmaceuticals
PHAT
$878M
| $105M | 6.96% |
10,109,279
| – | – |
|
|
6
BridgeBio Pharma
BBIO
$16B
| $71.9M | 4.77% |
2,725,949
+737,073
| +37% | +$20.9M |
|
7
Vaxcyte
PCVX
$7.99B
| $59.4M | 3.94% |
1,164,405
| – | – |
|
8
Rhythm Pharmaceuticals
RYTM
$7.28B
| $54.4M | 3.61% |
2,371,304
+204,082
| +9% | +$4.57M |
|
|
VRNA
9
DELISTED
Verona Pharma
VRNA
| $49.1M | 3.26% |
3,014,349
+70,000
| +2% | +$1.35M |
|
10
Crinetics Pharmaceuticals
CRNX
$8.88B
| $47.3M | 3.14% |
1,589,931
+175,108
| +12% | +$3.61M |
|
11
Arcutis Biotherapeutics
ARQT
$3.46B
| $46.1M | 3.06% |
8,684,232
| – | – |
|
|
ALPN
12
DELISTED
Alpine Immune Sciences Inc
ALPN
| $34.2M | 2.27% |
2,985,757
| – | – |
|
13
Tarsus Pharmaceuticals
TARS
$2.57B
| $31.8M | 2.11% |
1,787,527
| – | – |
|
|
KALV
14
DELISTED
KalVista Pharmaceuticals
KALV
| $31.2M | 2.07% |
3,238,859
| – | – |
|
15
Disc Medicine
IRON
$2.81B
| $30.8M | 2.04% |
655,000
| – | – |
|
|
16
Rocket Pharmaceuticals
RCKT
$380M
| $28.7M | 1.91% |
+1,403,013
| New | +$25.5M |
|
17
Revolution Medicines
RVMD
$37.9B
| $27.6M | 1.83% |
997,455
+142,971
| +17% | +$4.24M |
|
|
APLS
18
DELISTED
Apellis Pharmaceuticals
APLS
| $23.4M | 1.55% |
+614,043
| New | +$27M |
|
|
19
AN2 Therapeutics
ANTX
$169M
| $22.3M | 1.48% |
+1,388,889
| New | +$15.7M |
|
|
MRUS
20
DELISTED
Merus
MRUS
| $17.6M | 1.17% |
746,479
| – | – |
|
|
JBIO
21
Jade Biosciences
JBIO
$1.27B
| $16.4M | 1.09% |
34,425
+6,000
| +21% | +$3.25M |
|
22
AnaptysBio
ANAB
$1.6B
| $16.2M | 1.07% |
899,700
| – | – |
|
23
Savara
SVRA
$1.15B
| $15.1M | 1% |
+4,000,000
| New | +$14.3M |
|
24
Trevi Therapeutics
TRVI
$2.46B
| $15M | 1% |
6,881,090
| – | – |
|
25
Cogent Biosciences
COGT
$6.49B
| $14.6M | 0.97% |
1,501,383
| – | – |
|
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