FLSM

Frazier Life Sciences Management Portfolio holdings

AUM $2.5B
1-Year Est. Return 52.94%
This Quarter Est. Return
1 Year Est. Return
+52.94%
3 Year Est. Return
5 Year Est. Return
10 Year Est. Return
AUM
$2.19B
AUM Growth
-$221M
Cap. Flow
Cap. Flow %
Top 10 Hldgs %
Holding
54
New
Increased
Reduced
Closed

Top Buys

1
+$45.5M
2
+$15.5M
3
+$15.1M
4
ZLAB icon
Zai Lab
ZLAB
+$12.6M
5
MIRM icon
Mirum Pharmaceuticals
MIRM
+$10.1M

Top Sells

1
+$63.1M
2
+$33.9M
3
+$20.8M
4
KRYS icon
Krystal Biotech
KRYS
+$18M
5
PLRX icon
Pliant Therapeutics
PLRX
+$14.8M

Sector Composition

1 Healthcare 99.79%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
NAMS icon
1
NewAmsterdam Pharma
NAMS
$3.99B
$330M 15.08%
16,116,418
+200,000
MIRM icon
2
Mirum Pharmaceuticals
MIRM
$3.67B
$306M 13.99%
6,795,121
+224,729
VRNA
3
DELISTED
Verona Pharma
VRNA
$220M 10.03%
3,457,850
+73,900
ARQT icon
4
Arcutis Biotherapeutics
ARQT
$2.51B
$137M 6.28%
8,785,284
BBIO icon
5
BridgeBio Pharma
BBIO
$10.5B
$131M 6%
3,800,457
KRYS icon
6
Krystal Biotech
KRYS
$5.47B
$124M 5.67%
688,460
-100,000
IRON icon
7
Disc Medicine
IRON
$3.28B
$87.1M 3.98%
1,754,834
TARS icon
8
Tarsus Pharmaceuticals
TARS
$3.13B
$71.8M 3.28%
1,397,527
-190,000
TRVI icon
9
Trevi Therapeutics
TRVI
$1.27B
$64.5M 2.95%
10,259,409
-405,365
PHAT icon
10
Phathom Pharmaceuticals
PHAT
$939M
$63.4M 2.9%
10,109,279
KALV icon
11
KalVista Pharmaceuticals
KALV
$560M
$56.4M 2.58%
4,887,867
MAZE
12
Maze Therapeutics
MAZE
$1.26B
$45.5M 2.08%
+4,129,001
MBX
13
MBX Biosciences
MBX
$587M
$44.2M 2.02%
5,985,347
RYTM icon
14
Rhythm Pharmaceuticals
RYTM
$7.32B
$36M 1.64%
678,760
-1,191,048
SLNO icon
15
Soleno Therapeutics
SLNO
$3.54B
$35.7M 1.63%
499,159
-200,000
RVMD icon
16
Revolution Medicines
RVMD
$10.3B
$35.3M 1.61%
997,455
SVRA icon
17
Savara
SVRA
$612M
$31.8M 1.45%
11,462,301
+2,801,922
AGIO icon
18
Agios Pharmaceuticals
AGIO
$2.52B
$31.3M 1.43%
1,069,854
+100
ERAS icon
19
Erasca
ERAS
$704M
$30.9M 1.41%
22,575,851
+3,184,164
RARE icon
20
Ultragenyx Pharmaceutical
RARE
$3.23B
$23.9M 1.09%
658,715
ASND icon
21
Ascendis Pharma
ASND
$12.8B
$20.8M 0.95%
133,333
PCVX icon
22
Vaxcyte
PCVX
$5.62B
$20.4M 0.93%
539,405
ALKS icon
23
Alkermes
ALKS
$5.04B
$19.8M 0.91%
601,129
PVLA
24
Palvella Therapeutics
PVLA
$805M
$19.3M 0.88%
690,012
+36,120
CGON icon
25
CG Oncology
CGON
$3.18B
$18.9M 0.86%
770,000
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