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FLSM
Frazier Life Sciences Management Portfolio holdings
AUM
$3.89B
1-Year Est. Return
201.1%
This Fund
S&P 500
This Quarter
Est. Return
+18.89%
1 Year Est. Return
+201.1%
3 Year Est. Return
+879.31%
5 Year Est. Return
–
10 Year Est. Return
–
AUM
$2.5B
AUM Growth
+$357M
(+17%)
Cap. Flow
+$201M
Cap. Flow
% of AUM
8.05%
Top 10 Holdings %
Top 10 Hldgs %
59.89%
Holding
57
New
8
Increased
13
Reduced
5
Closed
4
Top Buys
| 1 |
MBX
MBX Biosciences
MBX
|
+$137M |
| 2 |
Ascendis Pharma A/S
ASND
|
+$18M |
| 3 |
ORKA
Oruka Therapeutics
ORKA
|
+$16.6M |
| 4 |
Alkermes
ALKS
|
+$15.4M |
| 5 |
Lexeo Therapeutics
LXEO
|
+$14.9M |
Top Sells
| 1 |
Edgewise Therapeutics
EWTX
|
+$17.9M |
| 2 |
CERE
Cerevel Therapeutics Holdings, Inc. Common Stock
CERE
|
+$16.1M |
| 3 |
Vaxcyte
PCVX
|
+$14.4M |
| 4 |
APLT
Applied Therapeutics
APLT
|
+$10.7M |
| 5 |
PepGen
PEPG
|
+$9.47M |
Sector Composition
| 1 | Healthcare | 99.86% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
1
Mirum Pharmaceuticals
MIRM
$7.19B
| $256M | 10.27% |
6,570,392
+75,000
| +1% | +$2.99M |
|
2
NewAmsterdam Pharma
NAMS
$3.7B
| $213M | 8.55% |
12,855,194
+628,251
| +5% | +$10.9M |
|
3
Phathom Pharmaceuticals
PHAT
$878M
| $183M | 7.33% |
10,109,279
| – | – |
|
4
Krystal Biotech
KRYS
$10.2B
| $180M | 7.21% |
988,460
| – | – |
|
|
MBX
5
MBX Biosciences
MBX
$2.81B
| $155M | 6.23% |
+5,985,347
| New | +$137M |
|
6
Rhythm Pharmaceuticals
RYTM
$7.28B
| $127M | 5.08% |
2,416,952
+45,648
| +2% | +$2.19M |
|
|
7
Vaxcyte
PCVX
$7.99B
| $100M | 4.03% |
879,405
-160,000
| -15% | -$14.4M |
|
|
VRNA
8
DELISTED
Verona Pharma
VRNA
| $97.4M | 3.9% |
3,383,950
+69,601
| +2% | +$1.71M |
|
9
BridgeBio Pharma
BBIO
$16B
| $95.7M | 3.84% |
3,760,457
+127,853
| +4% | +$3.36M |
|
10
Disc Medicine
IRON
$2.81B
| $86.2M | 3.46% |
1,754,834
| – | – |
|
11
Arcutis Biotherapeutics
ARQT
$3.46B
| $81.7M | 3.27% |
8,785,284
| – | – |
|
|
12
Edgewise Therapeutics
EWTX
$4.14B
| $75.6M | 3.03% |
2,832,867
-898,200
| -24% | -$17.9M |
|
13
AnaptysBio
ANAB
$1.6B
| $74M | 2.97% |
2,209,189
+43,598
| +2% | +$1.49M |
|
14
Erasca
ERAS
$6.01B
| $52.9M | 2.12% |
19,391,687
+3,175,471
| +20% | +$8.94M |
|
15
Tarsus Pharmaceuticals
TARS
$2.57B
| $52.2M | 2.09% |
1,587,527
| – | – |
|
16
Agios Pharmaceuticals
AGIO
$2.31B
| $46.4M | 1.86% |
1,044,154
+172,180
| +20% | +$7.82M |
|
17
Revolution Medicines
RVMD
$37.9B
| $45.2M | 1.81% |
997,455
| – | – |
|
|
SLNO
18
DELISTED
Soleno Therapeutics
SLNO
| $44.2M | 1.77% |
875,667
| – | – |
|
|
KALV
19
DELISTED
KalVista Pharmaceuticals
KALV
| $42.7M | 1.71% |
3,687,867
| – | – |
|
20
Oric Pharmaceuticals
ORIC
$1.09B
| $42.5M | 1.7% |
4,142,855
| – | – |
|
21
Ultragenyx Pharmaceutical
RARE
$2.97B
| $35.2M | 1.41% |
633,715
+208,715
| +49% | +$10.6M |
|
22
Savara
SVRA
$1.15B
| $34.6M | 1.39% |
8,157,385
| – | – |
|
23
CG Oncology
CGON
$6.15B
| $29.1M | 1.16% |
770,000
| – | – |
|
24
Rocket Pharmaceuticals
RCKT
$380M
| $27.4M | 1.1% |
1,485,630
-75,600
| -5% | -$1.55M |
|
25
Trevi Therapeutics
TRVI
$2.46B
| $24.7M | 0.99% |
7,381,090
| – | – |
|
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