FLSM

Frazier Life Sciences Management Portfolio holdings

AUM $2.5B
This Quarter Return
-4.79%
1 Year Return
+52.94%
3 Year Return
+530.54%
5 Year Return
–
10 Year Return
–
AUM
$1.06B
AUM Growth
+$1.06B
Cap. Flow
-$30.5M
Cap. Flow %
-2.88%
Top 10 Hldgs %
68.2%
Holding
44
New
2
Increased
8
Reduced
8
Closed
3

Top Buys

1
HLVX icon
HilleVax
HLVX
$101M
2
KDNY
Chinook Therapeutics, Inc. Common Stock
KDNY
$15.4M
3
KRYS icon
Krystal Biotech
KRYS
$15M
4
TARS icon
Tarsus Pharmaceuticals
TARS
$5.41M
5
CERE
Cerevel Therapeutics Holdings, Inc. Common Stock
CERE
$3.87M

Top Sells

1
SRRA
Sierra Oncology, Inc. Common Stock
SRRA
$80.9M
2
BCYC
Bicycle Therapeutics
BCYC
$26.5M
3
ISEE
IVERIC bio, Inc. Common Stock
ISEE
$21.7M
4
PCVX icon
Vaxcyte
PCVX
$11.4M
5
ALPN
Alpine Immune Sciences, Inc. Common Stock
ALPN
$10.2M

Sector Composition

1 Healthcare 98.6%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
ARQT icon
1
Arcutis Biotherapeutics
ARQT
$1.86B
$180M 16.96% 8,434,232 – –
HLVX icon
2
HilleVax
HLVX
$105M
$101M 9.58% +9,285,682 New +$101M
KRYS icon
3
Krystal Biotech
KRYS
$4.27B
$71.9M 6.79% 1,095,407 +229,157 +26% +$15M
MIRM icon
4
Mirum Pharmaceuticals
MIRM
$3.71B
$69.4M 6.55% 3,566,912 – –
KDNY
5
DELISTED
Chinook Therapeutics, Inc. Common Stock
KDNY
$62.9M 5.93% 3,595,026 +882,985 +33% +$15.4M
SNDX icon
6
Syndax Pharmaceuticals
SNDX
$1.41B
$61.5M 5.8% 3,195,403 – –
PHAT icon
7
Phathom Pharmaceuticals
PHAT
$864M
$49.2M 4.64% 5,827,415 – –
SRRA
8
DELISTED
Sierra Oncology, Inc. Common Stock
SRRA
$47.9M 4.52% 870,636 -1,471,562 -63% -$80.9M
IMGO
9
DELISTED
Imago BioSciences, Inc. Common stock
IMGO
$39.8M 3.75% 2,971,274 – –
PCVX icon
10
Vaxcyte
PCVX
$4B
$38.9M 3.67% 1,787,405 -522,149 -23% -$11.4M
CRNX icon
11
Crinetics Pharmaceuticals
CRNX
$2.92B
$26.4M 2.49% 1,414,823 – –
TARS icon
12
Tarsus Pharmaceuticals
TARS
$2.47B
$26.1M 2.46% 1,787,527 +370,370 +26% +$5.41M
ALPN
13
DELISTED
Alpine Immune Sciences, Inc. Common Stock
ALPN
$25.4M 2.4% 2,985,757 -1,200,000 -29% -$10.2M
TCDA
14
DELISTED
Tricida, Inc. Common Stock
TCDA
$20.2M 1.9% 2,082,093 – –
COGT icon
15
Cogent Biosciences
COGT
$1.69B
$18.9M 1.78% 2,094,154 -557,600 -21% -$5.03M
ANAB icon
16
AnaptysBio
ANAB
$569M
$18.3M 1.72% 899,700 – –
GRCL
17
DELISTED
Gracell Biotechnologies Inc. American Depositary Shares
GRCL
$17.1M 1.62% 3,111,551 -334,422 -10% -$1.84M
KALV icon
18
KalVista Pharmaceuticals
KALV
$678M
$15.5M 1.46% 1,572,192 – –
MRUS icon
19
Merus
MRUS
$4.98B
$15.3M 1.44% 673,979 +45,000 +7% +$1.02M
FLACU
20
DELISTED
Frazier Lifesciences Acquisition Corporation Unit
FLACU
$14.8M 1.4% 1,501,000 – –
REPL icon
21
Replimune Group
REPL
$422M
$14.1M 1.33% 806,267 +89,505 +12% +$1.56M
GRTS
22
DELISTED
Gritstone bio, Inc. Common Stock
GRTS
$12.7M 1.2% 5,237,348 – –
ARVN icon
23
Arvinas
ARVN
$568M
$12M 1.13% 285,331 +15,000 +6% +$631K
PASG icon
24
Passage Bio
PASG
$22.7M
$11.8M 1.12% 5,009,219 – –
VRDN icon
25
Viridian Therapeutics
VRDN
$1.5B
$11.3M 1.07% 980,302 -759,228 -44% -$8.78M
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