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FLSM
Frazier Life Sciences Management Portfolio holdings
AUM
$3.89B
1-Year Est. Return
201.1%
This Fund
S&P 500
This Quarter
Est. Return
+25.98%
1 Year Est. Return
+201.1%
3 Year Est. Return
+879.31%
5 Year Est. Return
–
10 Year Est. Return
–
AUM
$1.67B
AUM Growth
+$293M
(+21%)
Cap. Flow
+$59.1M
Cap. Flow
% of AUM
3.53%
Top 10 Holdings %
Top 10 Hldgs %
66.82%
Holding
53
New
4
Increased
12
Reduced
8
Closed
5
Top Buys
| 1 |
Disc Medicine
IRON
|
+$23.2M |
| 2 |
NewAmsterdam Pharma
NAMS
|
+$20.3M |
| 3 |
Phathom Pharmaceuticals
PHAT
|
+$19.6M |
| 4 |
Mirum Pharmaceuticals
MIRM
|
+$13.3M |
| 5 |
BridgeBio Pharma
BBIO
|
+$12.3M |
Top Sells
| 1 |
VECT
VectivBio Holding AG Ordinary Shares
VECT
|
+$11.6M |
| 2 |
Vaxcyte
PCVX
|
+$11M |
| 3 |
RNAM
Avidity Biosciences
RNAM
|
+$7.67M |
| 4 |
Cogent Biosciences
COGT
|
+$7.55M |
| 5 |
GRTS
Gritstone bio, Inc. Common Stock
GRTS
|
+$6.46M |
Sector Composition
| 1 | Healthcare | 99.94% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
|
HLVX
1
DELISTED
HilleVax
HLVX
| $168M | 10.04% |
9,781,472
| – | – |
|
|
KDNY
2
DELISTED
Chinook Therapeutics, Inc. Common Stock
KDNY
| $167M | 9.97% |
4,345,559
| – | – |
|
|
3
Phathom Pharmaceuticals
PHAT
$878M
| $145M | 8.65% |
10,109,279
+1,702,127
| +20% | +$19.6M |
|
|
4
NewAmsterdam Pharma
NAMS
$3.7B
| $129M | 7.72% |
10,871,803
+1,530,252
| +16% | +$20.3M |
|
5
Krystal Biotech
KRYS
$10.2B
| $116M | 6.94% |
990,260
+44,853
| +5% | +$4.58M |
|
|
6
Mirum Pharmaceuticals
MIRM
$7.18B
| $113M | 6.74% |
4,360,107
+500,000
| +13% | +$13.3M |
|
7
Arcutis Biotherapeutics
ARQT
$3.46B
| $82.8M | 4.94% |
8,684,232
| – | – |
|
8
Syndax Pharmaceuticals
SNDX
$2.04B
| $77.6M | 4.64% |
3,708,838
| – | – |
|
|
VRNA
9
DELISTED
Verona Pharma
VRNA
| $62.2M | 3.72% |
2,944,349
| – | – |
|
|
10
Vaxcyte
PCVX
$7.99B
| $58.2M | 3.47% |
1,164,405
-233,000
| -17% | -$11M |
|
11
Rhythm Pharmaceuticals
RYTM
$7.28B
| $35.7M | 2.13% |
2,167,222
+2,483
| +0.1% | +$44.8K |
|
|
12
BridgeBio Pharma
BBIO
$16B
| $34.2M | 2.04% |
1,988,876
+817,226
| +70% | +$12.3M |
|
13
Tarsus Pharmaceuticals
TARS
$2.57B
| $32.3M | 1.93% |
1,787,527
| – | – |
|
|
ALPN
14
DELISTED
Alpine Immune Sciences Inc
ALPN
| $30.7M | 1.83% |
2,985,757
| – | – |
|
|
KALV
15
DELISTED
KalVista Pharmaceuticals
KALV
| $29.1M | 1.74% |
3,238,859
| – | – |
|
|
16
Disc Medicine
IRON
$2.81B
| $29.1M | 1.74% |
+655,000
| New | +$23.2M |
|
17
Crinetics Pharmaceuticals
CRNX
$8.88B
| $25.5M | 1.52% |
1,414,823
| – | – |
|
18
Revolution Medicines
RVMD
$37.9B
| $22.9M | 1.37% |
854,484
| – | – |
|
|
THRX
19
DELISTED
Theseus Pharmaceuticals, Inc. Common Stock
THRX
| $21M | 1.25% |
2,248,194
| – | – |
|
20
Acadia Pharmaceuticals
ACAD
$4.42B
| $20.5M | 1.23% |
857,338
| – | – |
|
|
MRUS
21
DELISTED
Merus
MRUS
| $19.7M | 1.17% |
746,479
| – | – |
|
22
AnaptysBio
ANAB
$1.6B
| $18.3M | 1.09% |
899,700
| – | – |
|
|
23
Cogent Biosciences
COGT
$6.49B
| $17.8M | 1.06% |
1,501,383
-657,771
| -30% | -$7.55M |
|
24
Tyra Biosciences
TYRA
$1.88B
| $17.5M | 1.05% |
1,028,013
-393,297
| -28% | -$5.7M |
|
|
JBIO
25
Jade Biosciences
JBIO
$1.26B
| $17.1M | 1.02% |
28,425
+18,765
| +194% | +$12M |
|
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