Frazier Life Sciences Management’s Krystal Biotech KRYS Stock Holding History

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$124M	Sell	481,307 -7,153	-1%	-$1.9M	3.2%	9
2025 Q4	$120M	Sell	488,460 -200,000	-29%	-$42.1M	3.23%	9
2025 Q3	$122M	Hold	688,460	–	–	3.64%	7
2025 Q2	$94.6M	Hold	688,460	–	–	3.78%	7
2025 Q1	$124M	Sell	688,460 -100,000	-13%	-$16.8M	5.67%	6
2024 Q4	$124M	Sell	788,460 -200,000	-20%	-$35.5M	5.13%	4
2024 Q3	$180M	Hold	988,460	–	–	7.21%	4
2024 Q2	$182M	Hold	988,460	–	–	8.49%	3
2024 Q1	$176M	Hold	988,460	–	–	7.42%	2
2023 Q4	$123M	Hold	988,460	–	–	6.56%	4
2023 Q3	$115M	Sell	988,460 -1,800	-0.2%	-$220K	7.62%	3
2023 Q2	$116M	Buy	990,260 +44,853	+5%	+$4.58M	6.94%	5
2023 Q1	$75.7M	Sell	945,407 -54,330	-5%	-$4.27M	5.48%	7
2022 Q4	$79.2M	Sell	999,737 -18,651	-2%	-$1.38M	4.92%	8
2022 Q3	$71M	Sell	1,018,388 -77,019	-7%	-$5.56M	5.47%	7
2022 Q2	$71.9M	Buy	1,095,407 +229,157	+26%	+$14.3M	6.79%	3
2022 Q1	$57.6M	Buy	+866,250	New	+$54.1M	4.91%	5