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Krystal Biotech

264 hedge funds and large institutions have $4.35B invested in Krystal Biotech in 2024 Q4 according to their latest regulatory filings, with 37 funds opening new positions, 95 increasing their positions, 97 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

72% more call options, than puts

Call options by funds: $63.3M | Put options by funds: $36.8M

0% more funds holding in top 10

Funds holding in top 10: 66 (0)

2% less repeat investments, than reductions

Existing positions increased: 95 | Existing positions reduced: 97

1.87% less ownership

Funds ownership: 98.44%96.57% (-1.9%)

7% less funds holding

Funds holding: 283264 (-19)

15% less capital invested

Capital invested by funds: $5.15B → $4.35B (-$796M)

29% less first-time investments, than exits

New positions opened: 37 | Existing positions closed: 52

Holders
264
Holders Change
-19
Holders Change %
-6.71%
% of All Funds
3.48%
Holding in Top 10
6
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.08%
New
37
Increased
95
Reduced
97
Closed
52
Calls
$63.3M
Puts
$36.8M
Net Calls
+$26.5M
Net Calls Change
+$3.95M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$676M +$3.75M +21,133 +0.5%
BlackRock
2
BlackRock
New York
$632M +$7.23M +40,749 +1%
Vanguard Group
3
Vanguard Group
Pennsylvania
$451M +$5.09M +28,707 +1%
ACA
4
Avoro Capital Advisors
New York
$412M +$1.17M +6,600 +0.3%
State Street
5
State Street
Massachusetts
$200M -$30.8M -173,836 -12%
Capital World Investors
6
Capital World Investors
California
$138M +$21.3K +120 +0%
FLSM
7
Frazier Life Sciences Management
California
$124M -$35.5M -200,000 -20%
RG
8
Redmile Group
California
$118M -$10.1M -57,070 -7%
Geode Capital Management
9
Geode Capital Management
Massachusetts
$92.7M -$6.21K -35 -0%
Dimensional Fund Advisors
10
Dimensional Fund Advisors
Texas
$92.2M -$2.07M -11,662 -2%
HRCM
11
Hood River Capital Management
Florida
$80.3M +$1.88M +10,622 +2%
T. Rowe Price Associates
12
T. Rowe Price Associates
Maryland
$79.8M +$12.6M +71,200 +16%
SCM
13
Soleus Capital Management
Connecticut
$56.1M +$25.1M +141,400 +65%
N
14
Nuveen
North Carolina
$47.6M -$1.37M -7,740 -2%
Jennison Associates
15
Jennison Associates
New York
$47.5M -$18.9M -106,536 -26%
Goldman Sachs
16
Goldman Sachs
New York
$43.4M -$4.29M -24,179 -8%
Invesco
17
Invesco
Georgia
$43.1M -$16M -90,356 -25%
Northern Trust
18
Northern Trust
Illinois
$41.1M +$4.18M +23,572 +10%
Morgan Stanley
19
Morgan Stanley
New York
$40.1M -$3.46M -19,529 -7%
Charles Schwab
20
Charles Schwab
California
$38.1M +$524K +2,954 +1%
WP
21
Woodline Partners
California
$34.6M +$7.32M +41,287 +23%
Norges Bank
22
Norges Bank
Norway
$34.4M -$4.36M -24,569 -10%
Lord, Abbett & Co
23
Lord, Abbett & Co
New Jersey
$33.8M -$12.2M -68,531 -24%
UBS AM
24
UBS AM
Illinois
$32.9M -$2.62M -14,743 -7%
B
25
Braidwell
Connecticut
$31.4M +$5.64M +31,809 +19%

KRYS Hedge Fund Activity: Q4 2024 in Review

264 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in Krystal Biotech (KRYS) for Q4 2024, worth a combined $4.35B — down 15% from $5.15B a quarter earlier.

Sellers outnumbered buyers: 52 funds closed out of KRYS and 37 opened new positions — a net loss of 15 holders — while 97 trimmed existing stakes and 95 added.

The largest buyer was Soleus Capital Management, adding an estimated $25.1M. The largest seller was Frazier Life Sciences Management, cutting an estimated $35.5M.

  • 264 institutional investors held Krystal Biotech (KRYS) as of Q4 2024, down from 283 in Q3 2024.
  • Funds reported $4.35B of Krystal Biotech stock for Q4 2024, down 15% quarter-over-quarter.
  • 37 funds opened new Krystal Biotech positions in Q4 2024 and 52 closed out, a net change of -15 holders.
  • The largest Krystal Biotech buyer in Q4 2024 was Soleus Capital Management, an estimated $25.1M added.
  • The largest Krystal Biotech seller in Q4 2024 was Frazier Life Sciences Management, an estimated $35.5M sold.

Based on aggregated 13F filings for Q4 2024.