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Krystal Biotech

334 hedge funds and large institutions have $7.02B invested in Krystal Biotech in 2025 Q4 according to their latest regulatory filings, with 82 funds opening new positions, 112 increasing their positions, 104 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

204% more first-time investments, than exits

New positions opened: 82 | Existing positions closed: 27

145% more call options, than puts

Call options by funds: $53M | Put options by funds: $21.6M

42% more capital invested

Capital invested by funds: $4.94B → $7.02B (+$2.08B)

18% more funds holding

Funds holding: 284334 (+50)

14% more funds holding in top 10

Funds holding in top 10: 78 (+1)

1.39% more ownership

Funds ownership: 96.77%98.16% (+1.4%)

8% more repeat investments, than reductions

Existing positions increased: 112 | Existing positions reduced: 104

Holders
334
Holders Change
+50
Holders Change %
+17.61%
% of All Funds
4.06%
Holding in Top 10
8
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+14.29%
% of All Funds
0.1%
New
82
Increased
112
Reduced
104
Closed
27
Calls
$53M
Puts
$21.6M
Net Calls
+$31.3M
Net Calls Change
+$104M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$1.07B +$1.72M +8,181 +0.2%
BlackRock
2
BlackRock
New York
$971M +$21.8M +103,689 +3%
ACA
3
Avoro Capital Advisors
New York
$712M +$23.4M +111,111 +4%
Vanguard Group
4
Vanguard Group
Pennsylvania
$685M -$2.81M -13,363 -0.5%
State Street
5
State Street
Massachusetts
$331M -$11.3M -53,664 -4%
SCM
6
Soleus Capital Management
Connecticut
$232M -$16.4M -77,772 -8%
Capital World Investors
7
Capital World Investors
California
$200M +$54.7K +260 +0%
RG
8
Redmile Group
California
$167M +$3.43M +16,317 +2%
HRCM
9
Hood River Capital Management
Florida
$151M +$1.34M +6,356 +1%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$151M +$133K +634 +0.1%
T. Rowe Price Associates
11
T. Rowe Price Associates
Maryland
$131M +$13.2M +62,897 +13%
Dimensional Fund Advisors
12
Dimensional Fund Advisors
Texas
$122M -$8.63M -40,996 -8%
FLSM
13
Frazier Life Sciences Management
California
$120M -$42.1M -200,000 -29%
BG
14
Bellevue Group
Switzerland
$101M +$86.1M +409,011 +31,175%
Citadel Advisors
15
Citadel Advisors
Florida
$95.3M -$52.7M -250,483 -39%
William Blair Investment Management
16
William Blair Investment Management
Illinois
$92.8M +$47.8M +227,038 +152%
Goldman Sachs
17
Goldman Sachs
New York
$72.4M -$11.5M -54,725 -16%
Norges Bank
18
Norges Bank
Norway
$70.2M +$59.9M +284,573 New
Northern Trust
19
Northern Trust
Illinois
$61M -$152K -722 -0.3%
First Trust Advisors
20
First Trust Advisors
Illinois
$60.5M -$656K -3,116 -1%
Charles Schwab
21
Charles Schwab
California
$59.9M -$18.7K -89 -0%
Morgan Stanley
22
Morgan Stanley
New York
$54.6M -$2.76M -13,097 -6%
Janus Henderson Group
23
Janus Henderson Group
United Kingdom
$54.1M +$44.1M +209,369 +2,079%
B
24
Braidwell
Connecticut
$49.8M -$67M -318,300 -61%
Bank of America
25
Bank of America
North Carolina
$47M +$11.1M +52,812 +38%