KRYS icon

Krystal Biotech

154.22 USD
-1.49
0.96%
At close Updated Sep 16, 12:18 PM EDT
1 day
-0.96%
5 days
9.4%
1 month
5.41%
3 months
15.91%
6 months
-17.48%
Year to date
-1.46%
1 year
-20.62%
5 years
233.81%
10 years
1,349.44%
 

About: Krystal Biotech Inc is engaged in the healthcare sector in the United States. It is focused on the development of easy-to-use, redosable gene therapies to improve the lives of patients living with debilitating diseases. The company used its proprietary gene therapy platform, STAR-D to develop treatments for rare or orphan dermatological indications caused by the absence of or a mutation in a single gene. It plans to leverage its platform to expand its pipeline to include other dermatological indications in the future. The company has one operating segment, which is the business of developing and commercializing pharmaceutical products.

Employees: 275

0
Funds holding %
of 7,463 funds
0
Analysts bullish %
of 6 analysts

Fund manager confidence

Based on 2025 Q2 regulatory disclosures by fund managers ($100M+ AUM)

3% more repeat investments, than reductions

Existing positions increased: 100 | Existing positions reduced: 97

0.78% more ownership

Funds ownership: 94.91% [Q1] → 95.68% (+0.78%) [Q2]

0% more funds holding in top 10

Funds holding in top 10: 7 [Q1] → 7 (+0) [Q2]

9% less funds holding

Funds holding: 298 [Q1] → 272 (-26) [Q2]

11% less call options, than puts

Call options by funds: $60.6M | Put options by funds: $68M

23% less capital invested

Capital invested by funds: $4.93B [Q1] → $3.8B (-$1.13B) [Q2]

35% less first-time investments, than exits

New positions opened: 41 | Existing positions closed: 63

Research analyst outlook

6 Wall Street Analysts provided 1 year price targets over the past 3 months

Low target
$166
8% upside
Avg. target
$197
28% upside
High target
$240
56% upside

6 analyst ratings

positive
67%
neutral
33%
negative
0%
HC Wainwright & Co.
Joseph Pantginis
$240
Buy
Reiterated
15 Sep 2025
Chardan Capital
Geulah Livshits
$216
Buy
Maintained
22 Aug 2025
Citigroup
Yigal Nochomovitz
$166
Neutral
Maintained
5 Aug 2025
B of A Securities
Alec Stranahan
$192
Buy
Maintained
22 Jul 2025
Citigroup
Carly Kenselaar
$176
Neutral
Maintained
10 Jul 2025

Financial journalist opinion

Based on 5 articles about KRYS published over the past 30 days

Positive
Benzinga
22 hours ago
FDA Expands Krystal Biotech Vyjuvek's Label Allowing Newborns Access To Gene Therapy For Blistering Skin
The U.S. Food and Drug Administration (FDA) on Monday approved Krystal Biotech, Inc.'s KRYS label update for Vyjuvek (beremagene geperpavec-svdt).
FDA Expands Krystal Biotech Vyjuvek's Label Allowing Newborns Access To Gene Therapy For Blistering Skin
Neutral
GlobeNewsWire
yesterday
Krystal Biotech Announces FDA Approval of Updated VYJUVEK® Label
Revised label allows treatment of DEB patients from birth VYJUVEK can now be applied by patients and caregivers PITTSBURGH, Sept. 15, 2025 (GLOBE NEWSWIRE) -- Krystal Biotech, Inc. (the “Company”) (NASDAQ: KRYS) announced today that the United States Food and Drug Administration (FDA) approved a label update for VYJUVEK® (beremagene geperpavec-svdt) that expands the VYJUVEK eligible patient population to include dystrophic epidermolysis bullosa (DEB) patients from birth and provides patients full flexibility with respect to VYJUVEK application and managing wound dressings.
Krystal Biotech Announces FDA Approval of Updated VYJUVEK® Label
Positive
Zacks Investment Research
12 days ago
Krystal Biotech (KRYS) Up 8.5% Since Last Earnings Report: Can It Continue?
Krystal Biotech (KRYS) reported earnings 30 days ago. What's next for the stock?
Krystal Biotech (KRYS) Up 8.5% Since Last Earnings Report: Can It Continue?
Positive
Seeking Alpha
24 days ago
Krystal Biotech: A "Strong Buy" Despite KB707 Melanoma Tumor Targeting Update
I maintain a Strong Buy on Krystal Biotech, as the pause in melanoma trial enrollment is offset by promising progress in inhaled KB707 for NSCLC. Inhaled KB707 achieved a 36% ORR in heavily pretreated NSCLC patients, and an FDA end-of-Phase-2 meeting is scheduled for October 2025. Strong revenue growth from VYJUVEK and international launches, plus a robust pipeline, support long-term value despite near-term cash burn concerns.
Krystal Biotech: A "Strong Buy" Despite KB707 Melanoma Tumor Targeting Update
Neutral
GlobeNewsWire
26 days ago
Krystal Biotech Announces Update on Development Plans for Oncology Program KB707 and Prioritization of Inhaled KB707 for the Treatment of Non-Small Cell Lung Cancer
PITTSBURGH, Aug. 21, 2025 (GLOBE NEWSWIRE) -- Krystal Biotech, Inc. (the “Company”) (NASDAQ: KRYS), a commercial-stage biotechnology company, today announced an update on development plans for KB707, the Company's redosable immunotherapy designed to drive sustained, localized expression of interleukin-2 (IL-2) and interleukin-12 (IL-12) in the tumor microenvironment and promote systemic immune-mediated tumor clearance following inhaled or intratumoral delivery to solid tumors.
Krystal Biotech Announces Update on Development Plans for Oncology Program KB707 and Prioritization of Inhaled KB707 for the Treatment of Non-Small Cell Lung Cancer
Positive
Zacks Investment Research
1 month ago
KRYS Q2 Earnings and Sales Top Estimates, Stock Down on Q3 Outlook
Krystal Biotech tops Q2 estimates with strong Vyjuvek sales, but shares fall 14% on weak Q3 revenue guidance.
KRYS Q2 Earnings and Sales Top Estimates, Stock Down on Q3 Outlook
Neutral
Seeking Alpha
1 month ago
Krystal Biotech, Inc. (KRYS) Q2 2025 Earnings Call Transcript
Krystal Biotech, Inc. (NASDAQ:KRYS ) Q2 2025 Earnings Conference Call August 4, 2025 8:30 AM ET Company Participants Kathryn A. Romano - Executive VP & Chief Accounting Officer Krish S.
Krystal Biotech, Inc. (KRYS) Q2 2025 Earnings Call Transcript
Positive
Zacks Investment Research
1 month ago
Krystal Biotech, Inc. (KRYS) Tops Q2 Earnings and Revenue Estimates
Krystal Biotech, Inc. (KRYS) came out with quarterly earnings of $1.29 per share, beating the Zacks Consensus Estimate of $1.08 per share. This compares to earnings of $0.86 per share a year ago.
Krystal Biotech, Inc. (KRYS) Tops Q2 Earnings and Revenue Estimates
Positive
The Motley Fool
1 month ago
Krystal (KRYS) Q2 Profit Jumps 143%
Krystal (KRYS) Q2 Profit Jumps 143%
Krystal (KRYS) Q2 Profit Jumps 143%
Positive
Zacks Investment Research
1 month ago
Krystal Biotech, Inc. (KRYS) to Report Q2 Results: Wall Street Expects Earnings Growth
Krystal Biotech (KRYS) doesn't possess the right combination of the two key ingredients for a likely earnings beat in its upcoming report. Get prepared with the key expectations.
Krystal Biotech, Inc. (KRYS) to Report Q2 Results: Wall Street Expects Earnings Growth
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