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Krystal Biotech

367 hedge funds and large institutions have $7.32B invested in Krystal Biotech in 2026 Q1 according to their latest regulatory filings, with 76 funds opening new positions, 137 increasing their positions, 105 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

155% more call options, than puts

Call options by funds: $81M | Put options by funds: $31.8M

117% more first-time investments, than exits

New positions opened: 76 | Existing positions closed: 35

30% more repeat investments, than reductions

Existing positions increased: 137 | Existing positions reduced: 105

25% more funds holding in top 10

Funds holding in top 10: 810 (+2)

10% more funds holding

Funds holding: 334367 (+33)

4% more capital invested

Capital invested by funds: $7.02B → $7.32B (+$306M)

1.12% less ownership

Funds ownership: 98.16%97.04% (-1.1%)

Holders
367
Holders Change
+33
Holders Change %
+9.88%
% of All Funds
4.52%
Holding in Top 10
10
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+25%
% of All Funds
0.12%
New
76
Increased
137
Reduced
105
Closed
35
Calls
$81M
Puts
$31.8M
Net Calls
+$49.2M
Net Calls Change
+$17.9M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$1.13B +$6.48M +24,359 +0.6%
BlackRock
2
BlackRock
New York
$1.02B +$702K +2,639 +0.1%
ACA
3
Avoro Capital Advisors
New York
$746M
VPM
4
Vanguard Portfolio Management
Pennsylvania
$376M +$388M +1,456,727 New
State Street
5
State Street
Massachusetts
$340M -$7.42M -27,869 -2%
VCM
6
Vanguard Capital Management
Pennsylvania
$301M +$310M +1,165,324 New
SCM
7
Soleus Capital Management
Connecticut
$298M +$56.4M +212,028 +23%
Capital World Investors
8
Capital World Investors
California
$213M +$4.05M +15,220 +2%
RG
9
Redmile Group
California
$174M -$1.12M -4,200 -0.6%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$166M +$8.54M +32,097 +5%
HRCM
11
Hood River Capital Management
Florida
$160M +$1.67M +6,284 +1%
T. Rowe Price Associates
12
T. Rowe Price Associates
Maryland
$125M -$11.9M -44,881 -8%
BG
13
Bellevue Group
Switzerland
$124M +$19M +71,462 +17%
FLSM
14
Frazier Life Sciences Management
California
$124M -$1.9M -7,153 -1%
Dimensional Fund Advisors
15
Dimensional Fund Advisors
Texas
$121M -$6.38M -23,978 -5%
William Blair Investment Management
16
William Blair Investment Management
Illinois
$105M +$8.21M +30,838 +8%
First Trust Advisors
17
First Trust Advisors
Illinois
$90.5M +$28M +105,245 +43%
Janus Henderson Group
18
Janus Henderson Group
United Kingdom
$68.9M +$12.6M +47,219 +22%
Bank of America
19
Bank of America
North Carolina
$67.3M +$18.6M +69,840 +37%
Northern Trust
20
Northern Trust
Illinois
$65.2M +$1.34M +5,020 +2%
Invesco
21
Invesco
Georgia
$64.9M +$50.9M +191,365 +319%
Charles Schwab
22
Charles Schwab
California
$62.5M -$210K -788 -0.3%
Goldman Sachs
23
Goldman Sachs
New York
$55.5M -$20.9M -78,576 -27%
Morgan Stanley
24
Morgan Stanley
New York
$54M -$3.3M -12,399 -6%
B
25
Braidwell
Connecticut
$47.1M -$5.24M -19,676 -10%