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Krystal Biotech
KRYS

Overview Fund Activity

298 hedge funds and large institutions have $4.93B invested in Krystal Biotech in 2025 Q1 according to their latest regulatory filings, with 65 funds opening new positions, 87 increasing their positions, 112 reducing their positions, and 28 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
298
Holders Change
+35
Holders Change %
+13.31%
% of All Funds
4.05%
Holding in Top 10
7
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+16.67%
% of All Funds
0.1%
New
65
Increased
87
Reduced
112
Closed
28
Calls
$54.2M
Puts
$17.6M
Net Calls
+$36.5M
Net Calls Change
+$10M

Top Buyers

1
UBS AM
UBS AM
Illinois
+$65.9M
2
B
Braidwell
Connecticut
+$36.1M
3
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
+$33.5M
4
1832 Asset Management
1832 Asset Management
Ontario, Canada
+$24.5M
5
ACA
Avoro Capital Advisors
New York
+$18.4M

Top Sellers

1
Jennison Associates
Jennison Associates
New York
-$48.7M
2
Franklin Resources
Franklin Resources
California
-$29.8M
3
BBA
Baker Bros. Advisors
New York
-$26.6M
4
DCM
Driehaus Capital Management
Illinois
-$19.1M
5
FLSM
Frazier Life Sciences Management
California
-$18M
Name Holding Trade Value Shares
Change 		Shares
Change %
Fidelity Investments
1
Fidelity Investments
Massachusetts
$779M +$1.23M +6,818 +0.2%
BlackRock
2
BlackRock
New York
$711M -$16.4M -90,707 -2%
Vanguard Group
3
Vanguard Group
Pennsylvania
$509M -$9.59M -53,169 -2%
ACA
4
Avoro Capital Advisors
New York
$492M +$18.4M +102,178 +4%
State Street
5
State Street
Massachusetts
$221M -$9.42M -52,268 -4%
Capital World Investors
6
Capital World Investors
California
$172M +$13.6M +75,265 +9%
RG
7
Redmile Group
California
$133M -$2.79M -15,500 -2%
FLSM
8
Frazier Life Sciences Management
California
$124M -$18M -100,000 -13%
Geode Capital Management
9
Geode Capital Management
Massachusetts
$110M +$3.74M +20,757 +4%
UBS AM
10
UBS AM
Illinois
$104M +$65.9M +365,304 +174%
Dimensional Fund Advisors
11
Dimensional Fund Advisors
Texas
$96.3M -$9.86M -54,680 -9%
HRCM
12
Hood River Capital Management
Florida
$94.6M +$2.15M +11,918 +2%
SCM
13
Soleus Capital Management
Connecticut
$79.6M +$15M +83,379 +23%
T. Rowe Price Associates
14
T. Rowe Price Associates
Maryland
$74.1M -$17.8M -98,598 -19%
B
15
Braidwell
Connecticut
$72.3M +$36.1M +200,244 +100%
Morgan Stanley
16
Morgan Stanley
New York
$53.8M +$7.56M +41,930 +16%
Northern Trust
17
Northern Trust
Illinois
$46.9M -$409K -2,268 -0.9%
Invesco
18
Invesco
Georgia
$45.9M -$3.73M -20,709 -8%
Charles Schwab
19
Charles Schwab
California
$45.2M +$1.32M +7,344 +3%
NL
20
Nuveen LLC
North Carolina
$42.2M +$42.2M +234,180 New
Goldman Sachs
21
Goldman Sachs
New York
$42.1M -$7.85M -43,535 -16%
WP
22
Woodline Partners
California
$40M +$170K +941 +0.4%
T. Rowe Price Investment Management
23
T. Rowe Price Investment Management
Maryland
$33.5M +$33.5M +185,550 New
Bank of New York Mellon
24
Bank of New York Mellon
New York
$30.5M -$30.1K -167 -0.1%
Lord, Abbett & Co
25
Lord, Abbett & Co
New Jersey
$27.3M -$11.6M -64,403 -30%
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