OrbiMed’s Krystal Biotech KRYS Stock Holding History

OrbiMed’s Portfolio KRYS Stock Details KRYS Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$17.8M	Sell	69,100 -50,700	-42%	-$13.5M	0.39%	60
2025 Q4	$29.5M	Buy	119,800 +17,055	+17%	+$3.59M	0.6%	49
2025 Q3	$18.1M	Buy	102,745 +93,545	+1,017%	+$14M	0.44%	55
2025 Q2	$1.26M	Sell	9,200 -14,300	-61%	-$2.1M	0.03%	90
2025 Q1	$4.24M	Hold	23,500	–	–	0.1%	81
2024 Q4	$3.68M	Hold	23,500	–	–	0.08%	92
2024 Q3	$4.28M	Sell	23,500 -6,466	-22%	-$1.25M	0.08%	101
2024 Q2	$5.5M	Sell	29,966 -7,200	-19%	-$1.21M	0.11%	87
2024 Q1	$6.61M	Sell	37,166 -66,534	-64%	-$9.24M	0.12%	92
2023 Q4	$12.9M	Buy	+103,700	New	+$11.5M	0.26%	71
2020 Q1	–	Sell	-994,808	Closed	-$55.1M	–	154
2019 Q4	$55.1M	Buy	994,808 +392,858	+65%	+$19.3M	0.79%	41
2019 Q3	$20.9M	Sell	601,950 -40,056	-6%	-$1.79M	0.4%	61
2019 Q2	$25.9M	Buy	642,006 +582,796	+984%	+$19.1M	0.41%	59
2019 Q1	$1.95M	Buy	+59,210	New	+$1.4M	0.03%	116

Other funds holding KRYS

Fidelity Investments

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

BlackRock New York $5.7T AUM 30.48% 1-Year Est. Return

Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return

Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM

State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

Soleus Capital Management Greenwich, Connecticut $2.47B AUM 115.63% 1-Year Est. Return

Capital World Investors

Capital World Investors Los Angeles, California $733B AUM 35.63% 1-Year Est. Return

Redmile Group San Francisco, California $1.51B AUM 164.17% 1-Year Est. Return

Geode Capital Management

Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return