O

OrbiMed Portfolio holdings

AUM $4.59B
1-Year Est. Return 131.45%
This Fund
S&P 500
This Quarter Est. Return
1 Year Est. Return
+131.45%
3 Year Est. Return
5 Year Est. Return
10 Year Est. Return
AUM
$4.59B
AUM Growth
-$301M
Cap. Flow
Cap. Flow %
Top 10 Hldgs %
Holding
130
New
Increased
Reduced
Closed

Top Buys

1
+$109M
2
+$76.6M
3
+$43.7M
4
MLYS icon
Mineralys Therapeutics
MLYS
+$31.5M
5
QURE icon
uniQure
QURE
+$28.3M

Top Sells

1
+$87M
2
+$65.3M
3
+$61M
4
ALNY icon
Alnylam Pharmaceuticals
ALNY
+$57.8M
5
CI icon
Cigna
CI
+$56.4M

Sector Composition

1 Healthcare 99.49%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
EWTX icon
1
Edgewise Therapeutics
EWTX
$3.68B
$489M 10.66%
15,518,492
ELVN icon
2
Enliven Therapeutics
ELVN
$2.41B
$312M 6.8%
7,959,538
LLY icon
3
Eli Lilly
LLY
$985B
$218M 4.75%
236,800
-64,400
SVA
4
DELISTED
Sinovac Biotech, Ltd
SVA
$184M 4.02%
2,718,735
BSX icon
5
Boston Scientific
BSX
$71.8B
$149M 3.26%
2,382,100
-37,200
SION
6
Sionna Therapeutics
SION
$1.93B
$142M 3.09%
3,530,702
-30,953
AZN icon
7
AstraZeneca
AZN
$288B
$132M 2.88%
+670,200
MYGN icon
8
Myriad Genetics
MYGN
$375M
– –
0
MBX
9
MBX Biosciences
MBX
$1.5B
$109M 2.37%
3,637,887
-297,316
CRVS icon
10
Corvus Pharmaceuticals
CRVS
$1.04B
$105M 2.29%
7,165,006
ARGX icon
11
argenx
ARGX
$52B
$100M 2.18%
136,900
-9,100
EW icon
12
Edwards Lifesciences
EW
$49.8B
$98.5M 2.15%
1,230,600
-612,300
ISRG icon
13
Intuitive Surgical
ISRG
$150B
$96.2M 2.1%
208,700
-54,700
CMPX icon
14
Compass Therapeutics
CMPX
$429M
$80.5M 1.76%
15,219,994
MRK icon
15
Merck
MRK
$293B
$79.8M 1.74%
+663,400
GPCR icon
16
Structure Therapeutics
GPCR
$2.8B
$71.1M 1.55%
1,475,403
+313,600
AVBP icon
17
ArriVent BioPharma
AVBP
$1.41B
$69.8M 1.52%
3,027,328
IRON icon
18
Disc Medicine
IRON
$2.66B
$68.3M 1.49%
1,067,550
SPRY icon
19
ARS Pharmaceuticals
SPRY
$901M
$66.6M 1.45%
8,288,510
CGON icon
20
CG Oncology
CGON
$5.49B
$64.2M 1.4%
948,267
-568,283
XENE icon
21
Xenon Pharmaceuticals
XENE
$5.29B
$61.6M 1.34%
1,059,971
+612,771
SYK icon
22
Stryker
SYK
$117B
$60M 1.31%
182,500
-142,500
BMY icon
23
Bristol-Myers Squibb
BMY
$117B
$56.1M 1.22%
925,000
+150,000
MLYS icon
24
Mineralys Therapeutics
MLYS
$2.6B
$55.6M 1.21%
2,052,900
+1,072,500
PRAX icon
25
Praxis Precision Medicines
PRAX
$9.76B
$55.6M 1.21%
172,500
+78,000
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