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OrbiMed Portfolio holdings

AUM $4.59B
1-Year Est. Return 125.28%
This Fund
S&P 500
This Quarter Est. Return
+12.84%
1 Year Est. Return
+125.28%
3 Year Est. Return
+334.72%
5 Year Est. Return
+344.07%
10 Year Est. Return
+2,748.76%
AUM
$4.59B
AUM Growth
-$301M
Cap. Flow
-$430M
Cap. Flow %
-9.37%
Top 10 Hldgs %
42.8%
Holding
130
New
21
Increased
24
Reduced
35
Closed
20

Top Buys

1
AZN icon
AstraZeneca
AZN
+$129M
2
MRK icon
Merck
MRK
+$76.6M
3
GH icon
Guardant Health
GH
+$43.7M
4
MLYS icon
Mineralys Therapeutics
MLYS
+$31.5M
5
QURE icon
uniQure
QURE
+$28.3M

Top Sells

1
TERN
Terns Pharmaceuticals
TERN
+$87M
2
LLY icon
Eli Lilly
LLY
+$65.3M
3
APLS
Apellis Pharmaceuticals
APLS
+$61M
4
ALNY icon
Alnylam Pharmaceuticals
ALNY
+$57.8M
5
CI icon
Cigna
CI
+$56.4M

Sector Composition

1 Healthcare 99.49%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
KALV
101
DELISTED
KalVista Pharmaceuticals
KALV
$1.9M 0.04%
94,400
-288,000
-75% -$4.64M
IMA
102
ImageneBio Inc
IMA
$67.9M
$1.89M 0.04%
378,556
– –
VTGN icon
103
VistaGen Therapeutics
VTGN
$10.1M
$1.75M 0.04%
3,060,000
– –
ATAI icon
104
AtaiBeckley Inc
ATAI
$2.06B
$1.23M 0.03%
+347,000
New +$1.31M
TRAW icon
105
Traws Pharma
TRAW
$10.8M
$1.11M 0.02%
605,531
– –
APLS
106
DELISTED
Apellis Pharmaceuticals
APLS
– –
-2,429,868
Closed -$61M
BRKR icon
107
Bruker
BRKR
$9.14B
– –
-555,789
Closed -$26.2M
CELC icon
108
Celcuity
CELC
$4.54B
– –
-85,664
Closed -$8.54M
CI icon
109
Cigna
CI
$80.1B
– –
-205,000
Closed -$56.4M
CTMX icon
110
CytomX Therapeutics
CTMX
$779M
– –
-3,525,650
Closed -$15M
EXAS
111
DELISTED
Exact Sciences
EXAS
– –
-351,716
Closed -$35.7M
FOLD
112
DELISTED
Amicus Therapeutics
FOLD
– –
-729,900
Closed -$10.4M
INSM icon
113
Insmed
INSM
$23.6B
– –
-25,400
Closed -$4.42M
MDXH icon
114
MDxHealth
MDXH
$21.1M
– –
0
– –
NBIX icon
115
Neurocrine Biosciences
NBIX
$17.3B
– –
-314,240
Closed -$44.6M
OCUL icon
116
Ocular Therapeutix
OCUL
$2.14B
– –
-157,300
Closed -$1.91M
PMVP icon
117
PMV Pharmaceuticals
PMVP
$77.3M
– –
-4,975,291
Closed -$6.22M
QGEN icon
118
Qiagen
QGEN
$8.64B
– –
0
– –
RAPT
119
DELISTED
RAPT Therapeutics
RAPT
– –
-1,642,891
Closed -$55.6M
RNAM
120
DELISTED
Avidity Biosciences
RNAM
– –
-619,530
Closed -$44.7M
ROIV icon
121
Roivant Sciences
ROIV
$25B
– –
-2,190,907
Closed -$47.5M
RPTX
122
DELISTED
Repare Therapeutics
RPTX
– –
-3,322,488
Closed -$8.64M
SLNO
123
DELISTED
Soleno Therapeutics
SLNO
– –
0
– –
TARS icon
124
Tarsus Pharmaceuticals
TARS
$2.42B
– –
-154,400
Closed -$12.6M
TERN
125
DELISTED
Terns Pharmaceuticals
TERN
– –
-2,153,300
Closed -$87M
2 3 4
5
6

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