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OrbiMed Portfolio holdings

AUM $4.89B
1-Year Est. Return 87.75%
This Fund
S&P 500
This Quarter Est. Return
1 Year Est. Return
+87.75%
3 Year Est. Return
5 Year Est. Return
10 Year Est. Return
AUM
$4.89B
AUM Growth
+$717M
Cap. Flow
Cap. Flow %
Top 10 Hldgs %
Holding
126
New
Increased
Reduced
Closed

Top Buys

1
+$41.7M
2
+$37.3M
3
+$33.5M
4
HELP
Cybin Inc
HELP
+$24.7M
5
BRKR icon
Bruker
BRKR
+$23.5M

Top Sells

1
+$125M
2
+$65.8M
3
+$51.6M
4
AXSM icon
Axsome Therapeutics
AXSM
+$38.9M
5
SIBN icon
SI-BONE Inc
SIBN
+$38M

Sector Composition

1 Healthcare 99.56%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
JANX icon
51
Janux Therapeutics
JANX
$819M
$27M 0.55%
1,954,426
+188,326
TMO icon
52
Thermo Fisher Scientific
TMO
$196B
$26.9M 0.55%
46,500
BRKR icon
53
Bruker
BRKR
$6.09B
$26.2M 0.54%
+555,789
RYTM icon
54
Rhythm Pharmaceuticals
RYTM
$6.19B
$25.7M 0.53%
239,800
+24,648
STTK icon
55
Shattuck Labs
STTK
$248M
$23M 0.47%
6,306,127
ESPR icon
56
Esperion Therapeutics
ESPR
$801M
$22.1M 0.45%
+5,965,498
AVTX icon
57
Avalo Therapeutics
AVTX
$324M
$21.6M 0.44%
1,187,300
-162,000
LXEO icon
58
Lexeo Therapeutics
LXEO
$524M
$21.1M 0.43%
+2,125,000
ADCT icon
59
ADC Therapeutics
ADCT
$508M
$20.6M 0.42%
5,822,854
-84,497
URGN icon
60
UroGen Pharma
URGN
$1.02B
$20.5M 0.42%
875,487
+186,487
XENE icon
61
Xenon Pharmaceuticals
XENE
$3.34B
$20M 0.41%
447,200
+27,600
BTSG icon
62
BrightSpring Health Services
BTSG
$7.47B
$18.3M 0.37%
488,500
+224,700
VERA icon
63
Vera Therapeutics
VERA
$2.9B
$17.9M 0.37%
+353,500
QURE icon
64
uniQure
QURE
$974M
$17.6M 0.36%
737,400
+278,900
DFTX
65
Definium Therapeutics
DFTX
$1.72B
$16.4M 0.34%
1,226,700
+858,876
KROS icon
66
Keros Therapeutics
KROS
$432M
$16.4M 0.34%
804,212
-214,522
CARL
67
Carlsmed
CARL
$387M
$15.5M 0.32%
1,252,600
CTMX icon
68
CytomX Therapeutics
CTMX
$910M
$15M 0.31%
3,525,650
-4,935,850
VIR icon
69
Vir Biotechnology
VIR
$1.26B
$14.4M 0.29%
2,380,715
BCRX icon
70
BioCryst Pharmaceuticals
BCRX
$2.17B
$13.6M 0.28%
1,741,800
+840,300
COGT icon
71
Cogent Biosciences
COGT
$6.31B
$13.2M 0.27%
+371,000
CRBP icon
72
Corbus Pharmaceuticals
CRBP
$150M
$13M 0.27%
1,597,287
+425,000
TARS icon
73
Tarsus Pharmaceuticals
TARS
$3.21B
$12.6M 0.26%
154,400
-43,500
RLMD icon
74
Relmada Therapeutics
RLMD
$334M
$12.6M 0.26%
+2,610,600
TECX
75
Tectonic Therapeutic
TECX
$439M
$12M 0.25%
+574,600
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3
4 5