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OrbiMed Portfolio holdings

AUM $5.05B
1-Year Est. Return 125.28%
This Fund
S&P 500
This Quarter Est. Return
-15.61%
1 Year Est. Return
+125.28%
3 Year Est. Return
+334.72%
5 Year Est. Return
+344.07%
10 Year Est. Return
+2,748.76%
AUM
$5.41B
AUM Growth
-$2.89B
Cap. Flow
-$1.47B
Cap. Flow %
-27.24%
Top 10 Hldgs %
37.29%
Holding
165
New
19
Increased
15
Reduced
46
Closed
34

Sector Composition

Rank Sector Weight
1 Healthcare 95.11%
2 Financials 0.78%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
TCDA
1
DELISTED
Tricida, Inc. Common Stock
TCDA
$257M 4.75%
10,889,280
ASND icon
2
Ascendis Pharma A/S
ASND
$16.8B
$256M 4.74%
4,087,373
-68,518
-2% -$4.31M
BIIB icon
3
Biogen
BIIB
$32.1B
$251M 4.65%
835,249
-75,051
-8% -$24M
CELG
4
DELISTED
Celgene Corp
CELG
$209M 3.86%
3,256,700
+792,850
+32% +$58.5M
BSX icon
5
Boston Scientific
BSX
$68.3B
$205M 3.78%
5,790,400
-2,073,595
-26% -$75.2M
ALXN
6
DELISTED
Alexion Pharmaceuticals
ALXN
$199M 3.69%
2,047,400
-833,703
-29% -$98.5M
MRK icon
7
Merck
MRK
$324B
$191M 3.53%
2,614,760
-1,099,771
-30% -$77.6M
VRTX icon
8
Vertex Pharmaceuticals
VRTX
$125B
$188M 3.47%
1,133,200
-467,300
-29% -$81M
WMGI
9
DELISTED
Wright Medical Group Inc
WMGI
$134M 2.47%
4,905,899
-1,533,669
-24% -$42.4M
AGN
10
DELISTED
Allergan plc
AGN
$128M 2.37%
957,000
-193,405
-17% -$31.7M
CMTA
11
DELISTED
Clementia Pharmaceuticals Inc.
CMTA
$123M 2.27%
10,425,225
VTRS icon
12
Viatris
VTRS
$20.9B
$109M 2.02%
3,986,200
-793,400
-17% -$25.7M
TMO icon
13
Thermo Fisher Scientific
TMO
$215B
$97.9M 1.81%
437,500
-230,500
-35% -$54.1M
THOR
14
DELISTED
Synthorx, Inc. Common Stock
THOR
$92.4M 1.71%
+5,316,355
New +$77.1M
CI icon
15
Cigna
CI
$78.9B
$91.7M 1.7%
482,700
-151,200
-24% -$31.5M
SRPT icon
16
Sarepta Therapeutics
SRPT
$1.61B
$85.2M 1.58%
781,000
-73,400
-9% -$9.18M
REGN icon
17
Regeneron Pharmaceuticals
REGN
$73.1B
$83M 1.53%
222,100
-172,300
-44% -$63.1M
ISRG icon
18
Intuitive Surgical
ISRG
$128B
$81.7M 1.51%
511,500
+234,900
+85% +$39.8M
ELV icon
19
Elevance Health
ELV
$83.3B
$80.2M 1.48%
305,400
-168,600
-36% -$46.4M
INSP icon
20
Inspire Medical Systems
INSP
$1.49B
$77.3M 1.43%
1,829,449
-614,772
-25% -$26.1M
ILMN icon
21
Illumina
ILMN
$29.3B
$73.8M 1.36%
252,785
-22,205
-8% -$6.88M
PRNB
22
DELISTED
Principia Biopharma Inc. Common Stock
PRNB
$71.4M 1.32%
2,605,713
EW icon
23
Edwards Lifesciences
EW
$48.5B
$71.3M 1.32%
1,396,800
-1,575,000
-53% -$79.7M
IMMU
24
DELISTED
Immunomedics Inc
IMMU
$70.9M 1.31%
4,967,403
+638,830
+15% +$12.7M
LOGC
25
DELISTED
LogicBio Therapeutics, Inc. Common Stock
LOGC
$67.3M 1.24%
+6,466,783
New +$78.1M

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OrbiMed's Q4 2018 Portfolio in Review

As of Q4 2018, OrbiMed held 165 positions worth $5.41B, down 35% from $8.3B the previous quarter. Its ten largest holdings account for 37% of the portfolio.

OrbiMed withdrew a net $1.47B in Q4 2018, closing 34 positions and reducing 46 holdings. Its most notable exit was Jazz Pharmaceuticals, an estimated $149M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 95% of assets, up from 95% a quarter earlier, followed by Financials.

Against the trend, OrbiMed opened a new position in LogicBio Therapeutics, Inc. Common Stock worth $67.3M.

  • OrbiMed's largest Q4 2018 buy was LogicBio Therapeutics, Inc. Common Stock: 6,466,783 shares worth $67.3M.
  • OrbiMed added most to Celgene Corp in Q4 2018, an estimated $58.5M increase.
  • OrbiMed's biggest Q4 2018 reduction was Alexion Pharmaceuticals, cutting an estimated $98.5M.
  • OrbiMed fully exited Jazz Pharmaceuticals in Q4 2018, selling an estimated $149M.
  • OrbiMed's ten largest holdings make up 37% of its $5.41B portfolio in Q4 2018.
  • OrbiMed opened 19 new positions and closed 34 in Q4 2018.
  • OrbiMed's portfolio value fell 35% quarter-over-quarter to $5.41B.

Based on OrbiMed's 13F filing for Q4 2018, filed 14 Feb 2019.