O

OrbiMed Portfolio holdings

AUM $3.98B
This Quarter Return
+6.96%
1 Year Return
+13.05%
3 Year Return
+159.74%
5 Year Return
+207.27%
10 Year Return
+1,027.33%
AUM
$7.91B
AUM Growth
+$7.91B
Cap. Flow
+$959M
Cap. Flow %
12.12%
Top 10 Hldgs %
33.78%
Holding
159
New
26
Increased
22
Reduced
25
Closed
17

Top Buys

1
PRLD icon
Prelude Therapeutics
PRLD
$470M
2
PMVP icon
PMV Pharmaceuticals
PMVP
$260M
3
AFIB
Acutus Medical, Inc. Common Stock
AFIB
$163M
4
CALC icon
CalciMedica
CALC
$56.9M
5
TBPH icon
Theravance Biopharma
TBPH
$54.2M

Top Sells

1
ASND icon
Ascendis Pharma
ASND
$128M
2
CI icon
Cigna
CI
$82.5M
3
NTRA icon
Natera
NTRA
$81.6M
4
GKOS icon
Glaukos
GKOS
$46.5M
5
ALEC icon
Alector
ALEC
$34.2M

Sector Composition

1 Healthcare 98.49%
2 Financials 0.64%
3 Technology 0.57%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
PRLD icon
1
Prelude Therapeutics
PRLD
$68.5M
$470M 5.91% +15,594,877 New +$470M
SWTX
2
DELISTED
SpringWorks Therapeutics
SWTX
$353M 4.44% 7,406,307 – –
PMVP icon
3
PMV Pharmaceuticals
PMVP
$74.2M
$260M 3.27% +7,330,423 New +$260M
ALXN
4
DELISTED
Alexion Pharmaceuticals Inc
ALXN
$250M 3.14% 2,184,500 +28,500 +1% +$3.26M
TPTX
5
DELISTED
Turning Point Therapeutics, Inc. Common Stock
TPTX
$240M 3.01% 2,745,327 – –
HZNP
6
DELISTED
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
$234M 2.94% 3,008,755 +140,845 +5% +$10.9M
IOVA icon
7
Iovance Biotherapeutics
IOVA
$807M
$219M 2.75% 6,645,100 – –
MRTX
8
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$219M 2.75% 1,317,000 -7,100 -0.5% -$1.18M
MRK icon
9
Merck
MRK
$210B
$215M 2.7% 2,589,100 – –
BMY icon
10
Bristol-Myers Squibb
BMY
$96B
$214M 2.69% 3,549,100 +666,900 +23% +$40.2M
BIIB icon
11
Biogen
BIIB
$19.4B
$203M 2.55% 715,900 – –
BSX icon
12
Boston Scientific
BSX
$156B
$185M 2.33% 4,847,300 – –
VRTX icon
13
Vertex Pharmaceuticals
VRTX
$100B
$181M 2.28% 666,100 – –
AFIB
14
DELISTED
Acutus Medical, Inc. Common Stock
AFIB
$163M 2.05% +5,477,958 New +$163M
NTRA icon
15
Natera
NTRA
$23.1B
$152M 1.92% 2,110,700 -1,129,814 -35% -$81.6M
PRVL
16
DELISTED
Prevail Therapeutics Inc. Common Stock
PRVL
$141M 1.77% 13,822,463 – –
ARQT icon
17
Arcutis Biotherapeutics
ARQT
$1.86B
$137M 1.72% 4,673,850 – –
NBIX icon
18
Neurocrine Biosciences
NBIX
$13.8B
$125M 1.57% 1,301,715 +115,800 +10% +$11.1M
BNR
19
Burning Rock Biotech
BNR
$93.6M
$119M 1.5% 4,746,075 +4 +0% +$100
HUM icon
20
Humana
HUM
$36.5B
$116M 1.46% 280,300 – –
ASND icon
21
Ascendis Pharma
ASND
$11.8B
$113M 1.42% 734,500 -828,486 -53% -$128M
RPTX icon
22
Repare Therapeutics
RPTX
$71.7M
$105M 1.33% 3,426,325 – –
ETNB icon
23
89bio
ETNB
$1.34B
$95.7M 1.2% 3,729,442 -275,000 -7% -$7.06M
DXCM icon
24
DexCom
DXCM
$29.5B
$93.3M 1.17% 226,400 – –
TBPH icon
25
Theravance Biopharma
TBPH
$699M
$92M 1.16% 6,219,110 +3,664,640 +143% +$54.2M
1
2 3 4 5