O

OrbiMed Portfolio holdings

AUM $3.98B
This Quarter Return
+9.47%
1 Year Return
+13.05%
3 Year Return
+159.74%
5 Year Return
+207.27%
10 Year Return
+1,027.33%
AUM
$6.34B
AUM Growth
+$6.34B
Cap. Flow
-$66.5M
Cap. Flow %
-1.05%
Top 10 Hldgs %
40.11%
Holding
139
New
17
Increased
27
Reduced
20
Closed
14

Top Buys

1
PRVL
Prevail Therapeutics Inc. Common Stock
PRVL
$182M
2
TPTX
Turning Point Therapeutics, Inc. Common Stock
TPTX
$104M
3
QURE icon
uniQure
QURE
$70.2M
4
ATNX
Athenex, Inc. Common Stock
ATNX
$67.5M
5
NTRA icon
Natera
NTRA
$59.2M

Top Sells

1
CMTA
Clementia Pharmaceuticals Inc.
CMTA
$272M
2
GH icon
Guardant Health
GH
$118M
3
VTRS icon
Viatris
VTRS
$66.4M
4
TEVA icon
Teva Pharmaceuticals
TEVA
$64M
5
HUM icon
Humana
HUM
$55.9M

Sector Composition

1 Healthcare 97.38%
2 Financials 1.24%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
ASND icon
1
Ascendis Pharma
ASND
$11.8B
$443M 6.86% 3,846,673 -124,000 -3% -$14.3M
TCDA
2
DELISTED
Tricida, Inc. Common Stock
TCDA
$439M 6.79% 11,114,280 +225,000 +2% +$8.88M
BSX icon
3
Boston Scientific
BSX
$156B
$290M 4.49% 6,752,500 +962,100 +17% +$41.4M
ALXN
4
DELISTED
Alexion Pharmaceuticals Inc
ALXN
$252M 3.91% 1,926,085 -31,115 -2% -$4.08M
ALEC icon
5
Alector
ALEC
$238M
$250M 3.88% 13,182,329 – –
MRK icon
6
Merck
MRK
$210B
$216M 3.34% 2,570,100 – –
PRVL
7
DELISTED
Prevail Therapeutics Inc. Common Stock
PRVL
$182M 2.83% +13,822,463 New +$182M
VRTX icon
8
Vertex Pharmaceuticals
VRTX
$100B
$178M 2.76% 973,300 +18,000 +2% +$3.3M
NBIX icon
9
Neurocrine Biosciences
NBIX
$13.8B
$155M 2.4% 1,833,200 – –
IOVA icon
10
Iovance Biotherapeutics
IOVA
$807M
$136M 2.11% 5,548,326 – –
TMO icon
11
Thermo Fisher Scientific
TMO
$186B
$136M 2.1% 462,800 +15,500 +3% +$4.55M
EW icon
12
Edwards Lifesciences
EW
$47.8B
$132M 2.05% 715,000 – –
SRPT icon
13
Sarepta Therapeutics
SRPT
$1.78B
$126M 1.95% 828,400 – –
WMGI
14
DELISTED
Wright Medical Group Inc
WMGI
$125M 1.93% 4,187,799 – –
ISRG icon
15
Intuitive Surgical
ISRG
$170B
$110M 1.71% 210,300 – –
TPTX
16
DELISTED
Turning Point Therapeutics, Inc. Common Stock
TPTX
$104M 1.62% +2,567,550 New +$104M
ELV icon
17
Elevance Health
ELV
$71.8B
$102M 1.58% 361,600 +36,400 +11% +$10.3M
BHC icon
18
Bausch Health
BHC
$2.74B
$94.3M 1.46% 3,740,700 – –
PTCT icon
19
PTC Therapeutics
PTCT
$3.92B
$94M 1.46% 2,089,700 +570,000 +38% +$25.7M
INSP icon
20
Inspire Medical Systems
INSP
$2.77B
$89.2M 1.38% 1,471,000 – –
NTRA icon
21
Natera
NTRA
$23.1B
$88.9M 1.38% 3,224,328 +2,146,742 +199% +$59.2M
LOGC
22
DELISTED
LogicBio Therapeutics, Inc. Common Stock
LOGC
$84.1M 1.3% 6,466,783 – –
EXEL icon
23
Exelixis
EXEL
$10.1B
$83.6M 1.3% 3,912,900 +1,111,000 +40% +$23.7M
AVDR
24
DELISTED
Avedro, Inc Common Stock
AVDR
$83.3M 1.29% 4,240,128 – –
DCPH
25
DELISTED
Deciphera Pharmaceuticals, Inc. Common Stock
DCPH
$81.6M 1.26% 3,618,171 – –
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