FLSM

Frazier Life Sciences Management Portfolio holdings

AUM $3.34B
1-Year Est. Return 92.56%
This Quarter Est. Return
1 Year Est. Return
+92.56%
3 Year Est. Return
5 Year Est. Return
10 Year Est. Return
AUM
$3.34B
AUM Growth
+$837M
Cap. Flow
Cap. Flow %
Top 10 Hldgs %
Holding
53
New
Increased
Reduced
Closed

Top Buys

1
+$32.1M
2
+$18.5M
3
+$15.3M
4
ACAD icon
Acadia Pharmaceuticals
ACAD
+$13.1M
5
ASMB icon
Assembly Biosciences
ASMB
+$11.7M

Top Sells

1
+$21.1M
2
+$20M
3
+$14.6M
4
IRON icon
Disc Medicine
IRON
+$14.3M
5
TARS icon
Tarsus Pharmaceuticals
TARS
+$13.7M

Sector Composition

1 Healthcare 99.74%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
VALN
26
Valneva
VALN
$766M
$28M 0.84%
2,291,666
+833,333
RNA icon
27
Avidity Biosciences
RNA
$10.8B
$27.2M 0.82%
625,000
ASND icon
28
Ascendis Pharma
ASND
$12.9B
$26.5M 0.79%
133,333
ALKS icon
29
Alkermes
ALKS
$4.77B
$21M 0.63%
700,647
-300,000
MREO
30
Mereo BioPharma
MREO
$293M
$19.4M 0.58%
9,440,112
AKRO icon
31
Akero Therapeutics
AKRO
$4.48B
$17.4M 0.52%
366,784
PCVX icon
32
Vaxcyte
PCVX
$5.96B
$17.1M 0.51%
474,405
EOLS icon
33
Evolus
EOLS
$442M
$16.2M 0.48%
2,630,665
+195,115
DSGN icon
34
Design Therapeutics
DSGN
$510M
$14.7M 0.44%
1,953,547
IMCR icon
35
Immunocore
IMCR
$1.9B
$14M 0.42%
384,782
ACAD icon
36
Acadia Pharmaceuticals
ACAD
$4.2B
$13.1M 0.39%
+613,837
JBIO
37
Jade Biosciences
JBIO
$557M
$12.2M 0.37%
1,413,280
-358,836
ASMB icon
38
Assembly Biosciences
ASMB
$536M
$11.7M 0.35%
+456,249
ADVM icon
39
Adverum Biotechnologies
ADVM
$92.7M
$9.41M 0.28%
2,077,431
+1,008,187
TVTX icon
40
Travere Therapeutics
TVTX
$3.15B
$9.37M 0.28%
392,092
-610,000
NAMSW icon
41
NewAmsterdam Pharma Warrant
NAMSW
$137M
$8.56M 0.26%
500,333
ENGN icon
42
enGene Holdings
ENGN
$529M
$7.9M 0.24%
+1,157,380
AUTL
43
Autolus Therapeutics
AUTL
$367M
$7.54M 0.23%
4,623,324
MGNX icon
44
MacroGenics
MGNX
$92.4M
$5.34M 0.16%
3,175,665
SLN
45
Silence Therapeutics
SLN
$311M
$5.03M 0.15%
970,130
ALLO icon
46
Allogene Therapeutics
ALLO
$308M
$4.8M 0.14%
3,868,750
CBIO
47
Crescent Biopharma
CBIO
$239M
$3.25M 0.1%
272,951
-180,734
CGON icon
48
CG Oncology
CGON
$3.49B
– –
-770,000
COGT icon
49
Cogent Biosciences
COGT
$6.1B
– –
-1,734,601
ELEV
50
DELISTED
Elevation Oncology
ELEV
– –
-5,993,579
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