FLSM

Frazier Life Sciences Management Portfolio holdings

AUM $3.72B
1-Year Est. Return 129.71%
This Fund
S&P 500
This Quarter Est. Return
1 Year Est. Return
+129.71%
3 Year Est. Return
5 Year Est. Return
10 Year Est. Return
AUM
$3.72B
AUM Growth
+$386M
Cap. Flow
Cap. Flow %
Top 10 Hldgs %
Holding
52
New
Increased
Reduced
Closed

Top Buys

1
+$47.4M
2
+$30.5M
3
+$23.3M
4
RNAM
Avidity Biosciences
RNAM
+$23.1M
5
ACAD icon
Acadia Pharmaceuticals
ACAD
+$16.3M

Top Sells

1
+$361M
2
+$42.1M
3
+$32.8M
4
RARE icon
Ultragenyx Pharmaceutical
RARE
+$29.6M
5
BBIO icon
BridgeBio Pharma
BBIO
+$19.7M

Sector Composition

1 Healthcare 99.69%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
VOR icon
26
Vor Biopharma
VOR
$731M
$33.3M 0.89%
+2,543,939
ASND icon
27
Ascendis Pharma
ASND
$14.9B
$28.4M 0.76%
133,333
AURA icon
28
Aura Biosciences
AURA
$453M
$27.8M 0.75%
5,100,000
MNKD icon
29
MannKind Corp
MNKD
$849M
$24M 0.64%
+4,225,000
VALN
30
Valneva
VALN
$519M
$20.2M 0.54%
2,291,666
ALKS icon
31
Alkermes
ALKS
$5.61B
$19.6M 0.53%
700,647
EOLS icon
32
Evolus
EOLS
$295M
$17.5M 0.47%
2,630,665
IMCR icon
33
Immunocore
IMCR
$1.59B
$13.4M 0.36%
384,782
NAMSW icon
34
NewAmsterdam Pharma Warrant
NAMSW
$111M
$11.5M 0.31%
500,333
TVTX icon
35
Travere Therapeutics
TVTX
$3.65B
$9.23M 0.25%
241,592
-150,500
AUTL
36
Autolus Therapeutics
AUTL
$428M
$9.2M 0.25%
4,623,324
ALLO icon
37
Allogene Therapeutics
ALLO
$578M
$5.3M 0.14%
3,868,750
DSGN icon
38
Design Therapeutics
DSGN
$772M
$4.89M 0.13%
521,000
-1,432,547
XLO icon
39
Xilio Therapeutics
XLO
$48.3M
$3.79M 0.1%
+5,915,091
IBIO icon
40
iBio
IBIO
$72.9M
$3.77M 0.1%
+1,953,467
ADVM
41
DELISTED
Adverum Biotechnologies
ADVM
– –
-2,077,431
AKRO
42
DELISTED
Akero Therapeutics
AKRO
– –
-366,784
ASMB icon
43
Assembly Biosciences
ASMB
$465M
– –
-456,249
JBIO
44
Jade Biosciences
JBIO
$1.08B
– –
-1,413,280
ENGN icon
45
enGene Therapeutics Inc. Common Stock
ENGN
$541M
– –
-1,157,380
CBIO
46
Crescent Biopharma
CBIO
$592M
– –
-272,951
MGNX icon
47
MacroGenics
MGNX
$217M
– –
-3,175,665
MREO
48
Mereo BioPharma
MREO
$52.1M
– –
-9,440,112
PCVX icon
49
Vaxcyte
PCVX
$8.95B
– –
-474,405
RARE icon
50
Ultragenyx Pharmaceutical
RARE
$2.41B
– –
-983,715
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