|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$200M
|
+$18.3M
|
+460,858
|
+10%
|
|
|
2
|
Avoro Capital Advisors
New York
|
$189M
|
–
|
–
|
–
|
|
|
3
|
Driehaus Capital Management
Chicago,
Illinois
|
$183M
|
+$4.21M
|
+105,928
|
+2%
|
|
|
4
|
Polar Capital Holdings
London,
United Kingdom
|
$116M
|
+$209K
|
+5,253
|
+0.2%
|
|
|
5
|
Capital International Investors
Los Angeles,
California
|
$89.4M
|
–
|
–
|
–
|
|
|
6
|
Marshall Wace
London,
United Kingdom
|
$89.3M
|
-$6.64K
|
-167
|
-0%
|
|
|
7
|
Capital World Investors
Los Angeles,
California
|
$87.6M
|
–
|
–
|
–
|
|
|
8
|
Pictet Asset Management (Switzerland)
Geneva 73,
Switzerland
|
$78.3M
|
+$1.13M
|
+28,433
|
+1%
|
|
|
9
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$75.4M
|
+$6.99M
|
+175,929
|
+10%
|
|
|
10
|
Commodore Capital
New York
|
$71M
|
–
|
–
|
–
|
|
|
11
|
Braidwell
Stamford,
Connecticut
|
$70.4M
|
-$12.3M
|
-308,757
|
-14%
|
|
|
12
|
BVF Inc
San Francisco,
California
|
$70.4M
|
–
|
–
|
–
|
|
|
13
|
Perceptive Advisors
New York
|
$47.1M
|
-$24.2M
|
-608,797
|
-33%
|
|
|
14
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$45.4M
|
–
|
–
|
–
|
|
|
15
|
Redmile Group
San Francisco,
California
|
$43.1M
|
-$8.16M
|
-205,356
|
-15%
|
|
|
16
|
|
$42.2M
|
-$2.11M
|
-53,100
|
-5%
|
|
|
17
|
Wellington Management Group
Boston,
Massachusetts
|
$40.5M
|
+$31.9M
|
+803,614
|
+325%
|
|
|
18
|
|
$38.3M
|
+$3.77M
|
+94,886
|
+11%
|
|
|
19
|
Paradigm Biocapital Advisors
New York
|
$38.1M
|
+$13.4M
|
+338,259
|
+52%
|
|
|
20
|
|
$36.2M
|
-$8.71M
|
-219,085
|
-19%
|
|
|
21
|
Nicholas Investment Partners
Rancho Santa Fe,
California
|
$30.5M
|
+$14.1M
|
+354,403
|
+81%
|
|
|
22
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
$29M
|
-$280K
|
-7,041
|
-0.9%
|
|
|
23
|
Baker Bros. Advisors
New York
|
$28.9M
|
–
|
–
|
–
|
|
|
24
|
Holocene Advisors
New York
|
$27.4M
|
-$10.9M
|
-273,717
|
-28%
|
|
|
25
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$27.2M
|
-$530K
|
-13,322
|
-2%
|
|
