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Xenon Pharmaceuticals
XENE

Overview Fund Activity

203 hedge funds and large institutions have $2.59B invested in Xenon Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 40 funds opening new positions, 77 increasing their positions, 54 reducing their positions, and 39 closing their positions.

Holders
203
Holders Change
-3
Holders Change %
-1.46%
% of All Funds
2.73%
Holding in Top 10
10
Holding in Top 10 Change
-4
Holding in Top 10 Change %
-28.57%
% of All Funds
0.13%
New
40
Increased
77
Reduced
54
Closed
39
Calls
$8.93M
Puts
$7.08M
Net Calls
+$1.85M
Net Calls Change
-$6.04M

Top Buyers

1
BlackRock
1
BlackRock
New York
$168M
2
Holocene Advisors
2
Holocene Advisors
New York
$56.6M
3
State Street
3
State Street
Massachusetts
$43.2M
4
Geode Capital Management
4
Geode Capital Management
Massachusetts
$30.4M
5
B
5
Braidwell
Connecticut
$113M

Top Sellers

1
Wellington Management Group
1
Wellington Management Group
Massachusetts
$68.1M
2
Capital World Investors
2
Capital World Investors
California
$20.5M
3
SC
3
Samlyn Capital
New York
$0
4
T. Rowe Price Investment Management
4
T. Rowe Price Investment Management
Maryland
$2.41M
5
LGM
5
Logos Global Management
California
$0
Name Market Value Shares Shares
Change 		Shares
Change %
Fidelity Investments
1
Fidelity Investments
Massachusetts
$278M 8,884,363 +596,864 +7%
ACA
2
Avoro Capital Advisors
New York
$169M 5,400,000 -341,666 -6%
BlackRock
3
BlackRock
New York
$168M 5,365,327 +3,329,202 +164%
DCM
4
Driehaus Capital Management
Illinois
$136M 4,335,648 -249,211 -5%
B
5
Braidwell
Connecticut
$113M 3,605,029 +895,154 +33%
Janus Henderson Group
6
Janus Henderson Group
United Kingdom
$112M 3,577,735 +252,642 +8%
Capital International Investors
7
Capital International Investors
California
$99.6M 3,181,549 +92,819 +3%
CC
8
Commodore Capital
New York
$94.7M 3,025,000 +700,000 +30%
PCH
9
Polar Capital Holdings
United Kingdom
$84.6M 2,703,256 +80,217 +3%
Wellington Management Group
10
Wellington Management Group
Massachusetts
$68.1M 2,174,761 -1,614,436 -43%
VPC
11
Vestal Point Capital
New York
$62.6M 2,000,000 +700,000 +54%
Holocene Advisors
12
Holocene Advisors
New York
$56.6M 1,809,475 +1,809,475 New
AllianceBernstein
13
AllianceBernstein
Tennessee
$47.5M 1,518,527 +189,141 +14%
Pictet Asset Management
14
Pictet Asset Management
Switzerland
$46.2M 1,474,449 -3,168 -0.2%
State Street
15
State Street
Massachusetts
$43.2M 1,380,460 +1,074,840 +352%
DTC
16
Deep Track Capital
Connecticut
$42.3M 1,350,000 +350,000 +35%
Adage Capital Partners
17
Adage Capital Partners
Massachusetts
$40.4M 1,290,100 -624,649 -33%
JPMorgan Chase & Co
18
JPMorgan Chase & Co
New York
$39.3M 1,256,581 -101,021 -7%
Westfield Capital Management
19
Westfield Capital Management
Massachusetts
$36.1M 1,152,605 -238,765 -17%
AAA
20
Affinity Asset Advisors
New York
$34.4M 1,100,000 -228,175 -17%
Marshall Wace
21
Marshall Wace
United Kingdom
$31.9M 1,020,254 +262,109 +35%
Geode Capital Management
22
Geode Capital Management
Massachusetts
$30.4M 970,343 +900,746 +1,294%
O
23
OrbiMed
New York
$29.7M 947,877 – –
RSCM
24
Rock Springs Capital Management
Maryland
$29.2M 931,681 – –
Millennium Management
25
Millennium Management
New York
$27.6M 882,835 +648,779 +277%
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