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Xenon Pharmaceuticals

290 hedge funds and large institutions have $5.8B invested in Xenon Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 81 funds opening new positions, 124 increasing their positions, 60 reducing their positions, and 33 closing their positions.

New
Increased
Maintained
Reduced
Closed

145% more first-time investments, than exits

New positions opened: 81 | Existing positions closed: 33

107% more repeat investments, than reductions

Existing positions increased: 124 | Existing positions reduced: 60

53% more capital invested

Capital invested by funds: $3.78B → $5.8B (+$2.02B)

33% more funds holding in top 10

Funds holding in top 10: 912 (+3)

18% more funds holding

Funds holding: 246290 (+44)

11.18% more ownership

Funds ownership: 109.29%120.48% (+11%)

8% less call options, than puts

Call options by funds: $127M | Put options by funds: $138M

Holders
290
Holders Change
+44
Holders Change %
+17.89%
% of All Funds
3.57%
Holding in Top 10
12
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+33.33%
% of All Funds
0.15%
New
81
Increased
124
Reduced
60
Closed
33
Calls
$127M
Puts
$138M
Net Calls
-$11M
Net Calls Change
+$7.38M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$629M +$87.5M +1,898,241 +21%
ACA
2
Avoro Capital Advisors
New York
$336M +$16.3M +353,333 +7%
BlackRock
3
BlackRock
New York
$328M +$24.9M +539,834 +11%
Wellington Management Group
4
Wellington Management Group
Massachusetts
$281M +$2.99M +64,862 +1%
DCM
5
Driehaus Capital Management
Illinois
$261M -$2.17M -47,038 -1%
PCH
6
Polar Capital Holdings
United Kingdom
$256M +$89.4M +1,939,618 +79%
Janus Henderson Group
7
Janus Henderson Group
United Kingdom
$243M +$4.24M +91,948 +2%
Capital International Investors
8
Capital International Investors
California
$156M -$34.1M -740,232 -22%
Citadel Advisors
9
Citadel Advisors
Florida
$154M +$61.4M +1,331,777 +101%
JP Morgan Chase
10
JP Morgan Chase
New York
$107M +$19.8M +429,578 +29%
State Street
11
State Street
Massachusetts
$100M +$10.5M +227,983 +15%
AAA
12
Affinity Asset Advisors
New York
$97.4M +$19.6M +425,000 +34%
DM
13
Deerfield Management
New York
$94M +$49.5M +1,073,676 +198%
Holocene Advisors
14
Holocene Advisors
New York
$88.3M +$10.9M +236,605 +18%
Westfield Capital Management
15
Westfield Capital Management
Massachusetts
$81.5M +$8.05M +174,712 +14%
CP
16
Caligan Partners
New York
$81M +$38.9M +843,362 +153%
BNP Paribas Asset Management
17
BNP Paribas Asset Management
France
$78M +$13M +281,807 +27%
B
18
Braidwell
Connecticut
$77.8M -$22.4M -486,624 -27%
T. Rowe Price Associates
19
T. Rowe Price Associates
Maryland
$77.3M +$21.5M +467,291 +54%
Jennison Associates
20
Jennison Associates
New York
$76.7M +$1.23M +26,759 +2%
SL
21
Siren LLC
Connecticut
$76.7M +$23.3M +505,803 +62%
Alyeska Investment Group
22
Alyeska Investment Group
Illinois
$75.6M +$59.9M +1,299,469 New
Franklin Resources
23
Franklin Resources
California
$74.5M +$24.1M +522,518 +69%
Geode Capital Management
24
Geode Capital Management
Massachusetts
$63.5M +$6.46M +140,253 +15%
AllianceBernstein
25
AllianceBernstein
Tennessee
$62.9M -$8.78M -190,517 -12%