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Xenon Pharmaceuticals

246 hedge funds and large institutions have $3.78B invested in Xenon Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 51 funds opening new positions, 81 increasing their positions, 74 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

132% more first-time investments, than exits

New positions opened: 51 | Existing positions closed: 22

12% more funds holding

Funds holding: 219246 (+27)

12% more capital invested

Capital invested by funds: $3.39B → $3.78B (+$399M)

9% more repeat investments, than reductions

Existing positions increased: 81 | Existing positions reduced: 74

0% more funds holding in top 10

Funds holding in top 10: 99 (0)

0.06% less ownership

Funds ownership: 109.36%109.29% (-0.06%)

34% less call options, than puts

Call options by funds: $36.4M | Put options by funds: $54.7M

Holders
246
Holders Change
+27
Holders Change %
+12.33%
% of All Funds
2.99%
Holding in Top 10
9
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.11%
New
51
Increased
81
Reduced
74
Closed
22
Calls
$36.4M
Puts
$54.7M
Net Calls
-$18.4M
Net Calls Change
-$14.5M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$400M +$56.4K +1,343 +0%
ACA
2
Avoro Capital Advisors
New York
$243M +$1.03M +24,444 +0.5%
BlackRock
3
BlackRock
New York
$229M +$13.8M +329,333 +7%
Wellington Management Group
4
Wellington Management Group
Massachusetts
$214M +$48.5M +1,154,922 +32%
DCM
5
Driehaus Capital Management
Illinois
$203M +$15.5M +369,577 +9%
Janus Henderson Group
6
Janus Henderson Group
United Kingdom
$183M +$5.89M +140,149 +4%
Capital International Investors
7
Capital International Investors
California
$153M +$9.81M +233,466 +7%
PCH
8
Polar Capital Holdings
United Kingdom
$111M -$3.4M -81,072 -3%
B
9
Braidwell
Connecticut
$81.8M -$74.8M -1,779,953 -49%
CC
10
Commodore Capital
New York
$80.7M -$37.8M -900,000 -33%
AllianceBernstein
11
AllianceBernstein
Tennessee
$71.4M -$2.55M -60,603 -4%
JP Morgan Chase
12
JP Morgan Chase
New York
$67M +$3.99M +94,999 +7%
State Street
13
State Street
Massachusetts
$66.9M +$1.1M +26,083 +2%
Citadel Advisors
14
Citadel Advisors
Florida
$59.2M +$15.2M +362,115 +38%
Jennison Associates
15
Jennison Associates
New York
$57.9M +$6.59M +156,820 +14%
Holocene Advisors
16
Holocene Advisors
New York
$57.5M -$29.2M -694,472 -35%
AAA
17
Affinity Asset Advisors
New York
$56M -$6.3M -150,000 -11%
Westfield Capital Management
18
Westfield Capital Management
Massachusetts
$55M +$870K +20,705 +2%
BNP Paribas Asset Management
19
BNP Paribas Asset Management
France
$47.5M +$16.4M +389,964 +58%
Geode Capital Management
20
Geode Capital Management
Massachusetts
$42.7M -$1.04M -24,756 -3%
T. Rowe Price Associates
21
T. Rowe Price Associates
Maryland
$38.6M +$34.5M +820,608 +1,968%
SL
22
Siren LLC
Connecticut
$36.4M
FTM
23
First Turn Management
California
$35.8M
RSCM
24
Rock Springs Capital Management
Maryland
$35.3M -$2.69M -63,956 -8%
Franklin Resources
25
Franklin Resources
California
$34M +$2.61M +62,159 +9%