Avoro Capital Advisors’s Xenon Pharmaceuticals XENE Stock Holding History

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$336M	Buy	5,777,777 +353,333	+7%	+$16.3M	3.31%	11
2025 Q4	$243M	Buy	5,424,444 +24,444	+0.5%	+$1.03M	2.39%	15
2025 Q3	$217M	Hold	5,400,000	–	–	2.8%	13
2025 Q2	$169M	Sell	5,400,000 -341,666	-6%	-$11.1M	2.96%	12
2025 Q1	$193M	Buy	5,741,666 +75,000	+1%	+$2.85M	3.01%	9
2024 Q4	$222M	Hold	5,666,666	–	–	3.14%	10
2024 Q3	$223M	Hold	5,666,666	–	–	3.25%	11
2024 Q2	$221M	Hold	5,666,666	–	–	2.94%	14
2024 Q1	$244M	Hold	5,666,666	–	–	2.85%	14
2023 Q4	$261M	Buy	5,666,666 +766,666	+16%	+$27.1M	3.61%	14
2023 Q3	$167M	Hold	4,900,000	–	–	2.61%	14
2023 Q2	$189M	Hold	4,900,000	–	–	2.56%	15
2023 Q1	$175M	Hold	4,900,000	–	–	2.6%	13
2022 Q4	$193M	Hold	4,900,000	–	–	2.89%	13
2022 Q3	$177M	Hold	4,900,000	–	–	3.27%	12
2022 Q2	$149M	Sell	4,900,000 -85,000	-2%	-$2.57M	2.95%	12
2022 Q1	$152M	Hold	4,985,000	–	–	2.78%	13
2021 Q4	$156M	Buy	4,985,000 +1,335,000	+37%	+$39.9M	2.65%	12
2021 Q3	$55.8M	Hold	3,650,000	–	–	0.88%	22
2021 Q2	$68M	Hold	3,650,000	–	–	1.18%	18
2021 Q1	$65.3M	Buy	3,650,000 +850,000	+30%	+$14.4M	1.13%	19
2020 Q4	$43.1M	Hold	2,800,000	–	–	0.74%	26
2020 Q3	$31M	Hold	2,800,000	–	–	0.44%	29
2020 Q2	$35.1M	Buy	2,800,000 +28,000	+1%	+$356K	0.69%	29
2020 Q1	$31.4M	Buy	2,772,000 +372,000	+16%	+$5.3M	1.06%	22
2019 Q4	$31.5M	Hold	2,400,000	–	–	0.93%	20
2019 Q3	$21.6M	Hold	2,400,000	–	–	0.9%	24
2019 Q2	$23.7M	Hold	2,400,000	–	–	0.82%	24
2019 Q1	$24.4M	Hold	2,400,000	–	–	1.06%	21
2018 Q4	$15.1M	Buy	2,400,000 +32,782	+1%	+$291K	0.91%	21
2018 Q3	$31.2M	Buy	2,367,218 +1,165,100	+97%	+$13.5M	1.44%	19
2018 Q2	$11.1M	Buy	+1,202,118	New	+$7.47M	0.43%	33