|
1
|
Avoro Capital Advisors
New York
|
$177M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$169M
|
+$3.5M
|
+97,391
|
+2%
|
|
|
3
|
Driehaus Capital Management
Chicago,
Illinois
|
$163M
|
+$4.06M
|
+112,982
|
+3%
|
|
|
4
|
Marshall Wace
London,
United Kingdom
|
$101M
|
+$29.5M
|
+820,723
|
+41%
|
|
|
5
|
Polar Capital Holdings
London,
United Kingdom
|
$96.1M
|
+$4.41M
|
+122,663
|
+5%
|
|
|
6
|
Redmile Group
San Francisco,
California
|
$85.6M
|
+$26.3M
|
+731,270
|
+45%
|
|
|
7
|
Pictet Asset Management (Switzerland)
Geneva 73,
Switzerland
|
$82.6M
|
+$16.8M
|
+467,889
|
+26%
|
|
|
8
|
Capital World Investors
Los Angeles,
California
|
$82.1M
|
–
|
–
|
–
|
|
|
9
|
Perceptive Advisors
New York
|
$76.6M
|
–
|
–
|
–
|
|
|
10
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$69.1M
|
+$2.02M
|
+56,265
|
+3%
|
|
|
11
|
Holocene Advisors
New York
|
$66M
|
–
|
–
|
–
|
|
|
12
|
Capital International Investors
Los Angeles,
California
|
$59.3M
|
+$2.16M
|
+60,000
|
+4%
|
|
|
13
|
Point72 Asset Management
Stamford,
Connecticut
|
$59.2M
|
+$26.6M
|
+738,566
|
+82%
|
|
|
14
|
Commodore Capital
New York
|
$57.6M
|
–
|
–
|
–
|
|
|
15
|
|
$46.5M
|
+$6.21M
|
+172,797
|
+15%
|
|
|
16
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$41.7M
|
+$1.16M
|
+32,357
|
+3%
|
|
|
17
|
Citadel Advisors
Miami,
Florida
|
$41.2M
|
-$18.2M
|
-506,037
|
-31%
|
|
|
18
|
|
$41.1M
|
-$6.9M
|
-191,900
|
-14%
|
|
|
19
|
|
$37.6M
|
+$6.26M
|
+174,239
|
+20%
|
|
|
20
|
BVF Inc
San Francisco,
California
|
$32.5M
|
-$25.1M
|
-696,871
|
-44%
|
|
|
21
|
Great Point Partners
Greenwich,
Connecticut
|
$30.7M
|
-$9.14M
|
-254,334
|
-23%
|
|
|
22
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$27.5M
|
-$3.68M
|
-102,256
|
-12%
|
|
|
23
|
Baker Bros. Advisors
New York
|
$27.1M
|
–
|
–
|
–
|
|
|
24
|
Adage Capital Partners
Boston,
Massachusetts
|
$24.4M
|
+$1.62M
|
+45,000
|
+7%
|
|
|
25
|
Eventide Asset Management
Boston,
Massachusetts
|
$23.1M
|
+$6.17M
|
+171,500
|
+37%
|
|
