|
1
|
BVF Inc
San Francisco,
California
|
$25.2M
|
+$10.3M
|
+1,333,333
|
+75%
|
|
|
2
|
Capital World Investors
Los Angeles,
California
|
$8.34M
|
–
|
–
|
–
|
|
|
3
|
|
$8.1M
|
+$7.72M
|
+1,000,000
|
New
|
|
|
4
|
Perceptive Advisors
New York
|
$6.18M
|
+$2.55M
|
+330,000
|
+76%
|
|
|
5
|
Tekla Capital Management
Boston,
Massachusetts
|
$5.67M
|
+$5.41M
|
+700,000
|
New
|
|
|
6
|
DAFNA Capital Management
Los Angeles,
California
|
$4.16M
|
+$2.32M
|
+300,000
|
+140%
|
|
|
7
|
Invesco Private Capital
New York
|
$3.34M
|
-$185K
|
-23,905
|
-5%
|
|
|
8
|
Opaleye Management
Boston,
Massachusetts
|
$3.32M
|
–
|
–
|
–
|
|
|
9
|
Royal Bank of Canada
Toronto,
Ontario, Canada
|
$2.98M
|
-$194K
|
-25,173
|
-6%
|
|
|
10
|
Point72 Asset Management
Stamford,
Connecticut
|
$2.9M
|
–
|
–
|
–
|
|
|
11
|
Ghost Tree Capital
New York
|
$2.63M
|
+$2.51M
|
+325,000
|
New
|
|
|
12
|
Highland Capital Management (Texas)
Dallas,
Texas
|
$2.02M
|
+$1.93M
|
+250,000
|
New
|
|
|
13
|
Sphera Funds Management
Tel Aviv,
Israel
|
$1.85M
|
+$1.76M
|
+228,029
|
New
|
|
|
14
|
Novo Holdings A/S
Hellerup,
Denmark
|
$1.03M
|
–
|
–
|
–
|
|
|
15
|
Renaissance Technologies
New York
|
$779K
|
+$368K
|
+47,700
|
+98%
|
|
|
16
|
State of New Jersey Common Pension Fund D
Trenton,
New Jersey
|
$527K
|
–
|
–
|
–
|
|
|
17
|
Weiss Multi-Strategy Advisers
New York
|
$255K
|
-$6.95K
|
-900
|
-3%
|
|
|
18
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$232K
|
+$194K
|
+25,102
|
+688%
|
|
|
19
|
Monashee Investment Management
Boston,
Massachusetts
|
$203K
|
–
|
–
|
–
|
|
|
20
|
Leith Wheeler Investment Counsel
Vancouver,
British Columbia, Canada
|
$171K
|
-$13.9K
|
-1,794
|
-10%
|
|
|
21
|
Scotia Capital
Toronto,
Ontario, Canada
|
$169K
|
+$161K
|
+20,820
|
New
|
|
|
22
|
NJ State Employees Deferred Compensation Plan
Trenton,
New Jersey
|
$162K
|
–
|
–
|
–
|
|
|
23
|
K2 Principal Fund
Toronto,
Ontario, Canada
|
$122K
|
+$116K
|
+15,000
|
New
|
|
|
24
|
M&T Bank
Buffalo,
New York
|
$115K
|
+$110K
|
+14,251
|
New
|
|
|
25
|
Bank of Montreal
Toronto,
Ontario, Canada
|
$58K
|
–
|
–
|
–
|
|
