|
1
|
Avoro Capital Advisors
New York
|
$193M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$185M
|
+$767K
|
+21,070
|
+0.5%
|
|
|
3
|
Driehaus Capital Management
Chicago,
Illinois
|
$185M
|
+$6.47M
|
+177,777
|
+4%
|
|
|
4
|
Polar Capital Holdings
London,
United Kingdom
|
$120M
|
+$14M
|
+383,152
|
+14%
|
|
|
5
|
Marshall Wace
London,
United Kingdom
|
$93.3M
|
-$16.2M
|
-444,917
|
-16%
|
|
|
6
|
Redmile Group
San Francisco,
California
|
$93.1M
|
-$371K
|
-10,200
|
-0.4%
|
|
|
7
|
Capital World Investors
Los Angeles,
California
|
$89.7M
|
–
|
–
|
–
|
|
|
8
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$83.7M
|
+$7.65M
|
+210,148
|
+11%
|
|
|
9
|
Pictet Asset Management (Switzerland)
Geneva 73,
Switzerland
|
$83.6M
|
-$6.11M
|
-167,746
|
-7%
|
|
|
10
|
Capital International Investors
Los Angeles,
California
|
$82.8M
|
+$16.6M
|
+457,071
|
+28%
|
|
|
11
|
Perceptive Advisors
New York
|
$75.8M
|
-$7.33M
|
-201,262
|
-9%
|
|
|
12
|
Commodore Capital
New York
|
$65.4M
|
+$2.34M
|
+64,179
|
+4%
|
|
|
13
|
Braidwell
Stamford,
Connecticut
|
$61M
|
+$56.4M
|
+1,548,110
|
New
|
|
|
14
|
BVF Inc
San Francisco,
California
|
$50.1M
|
+$13.5M
|
+370,148
|
+41%
|
|
|
15
|
|
$47.1M
|
-$3.47M
|
-95,419
|
-7%
|
|
|
16
|
Holocene Advisors
New York
|
$47M
|
-$23.2M
|
-637,514
|
-35%
|
|
|
17
|
Point72 Asset Management
Stamford,
Connecticut
|
$46.5M
|
-$16.8M
|
-461,748
|
-28%
|
|
|
18
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$46.4M
|
+$718K
|
+19,711
|
+2%
|
|
|
19
|
Citadel Advisors
Miami,
Florida
|
$45.9M
|
+$816K
|
+22,405
|
+2%
|
|
|
20
|
|
$45.3M
|
+$430K
|
+11,800
|
+1%
|
|
|
21
|
|
$36.5M
|
-$4.26M
|
-116,906
|
-11%
|
|
|
22
|
Logos Global Management
San Francisco,
California
|
$35.5M
|
+$14.6M
|
+400,000
|
+80%
|
|
|
23
|
Great Point Partners
Greenwich,
Connecticut
|
$33.5M
|
–
|
–
|
–
|
|
|
24
|
Baker Bros. Advisors
New York
|
$29.6M
|
–
|
–
|
–
|
|
|
25
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$29M
|
-$910K
|
-25,000
|
-3%
|
|
