|
1
|
BVF Inc
San Francisco,
California
|
$11.8M
|
-$739K
|
-94,011
|
-3%
|
|
|
2
|
Capital World Investors
Los Angeles,
California
|
$5.72M
|
+$1.6M
|
+204,000
|
+17%
|
|
|
3
|
Perceptive Advisors
New York
|
$2.9M
|
-$129K
|
-16,419
|
-2%
|
|
|
4
|
|
$2.54M
|
-$2.87M
|
-365,188
|
-37%
|
|
|
5
|
Alyeska Investment Group
Chicago,
Illinois
|
$1.76M
|
+$3.46M
|
+439,894
|
New
|
|
|
6
|
Invesco Private Capital
New York
|
$1.52M
|
-$156K
|
-19,893
|
-5%
|
|
|
7
|
Opaleye Management
Boston,
Massachusetts
|
$1.44M
|
-$354K
|
-45,000
|
-11%
|
|
|
8
|
Tekla Capital Management
Boston,
Massachusetts
|
$1.4M
|
-$2.75M
|
-350,000
|
-50%
|
|
|
9
|
Endurant Capital Management
San Mateo,
California
|
$1.36M
|
+$2.68M
|
+340,672
|
New
|
|
|
10
|
DAFNA Capital Management
Los Angeles,
California
|
$1.36M
|
-$1.37M
|
-174,477
|
-34%
|
|
|
11
|
Sphera Funds Management
Tel Aviv,
Israel
|
$1.31M
|
–
|
–
|
–
|
|
|
12
|
Point72 Asset Management
Stamford,
Connecticut
|
$1.24M
|
–
|
–
|
–
|
|
|
13
|
Sabby Management
Miami Beach,
Florida
|
$1.19M
|
+$2.33M
|
+296,478
|
New
|
|
|
14
|
Renaissance Technologies
New York
|
$868K
|
+$809K
|
+102,890
|
+90%
|
|
|
15
|
Ghost Tree Capital
New York
|
$600K
|
-$1.38M
|
-175,000
|
-54%
|
|
|
16
|
|
$600K
|
+$1.18M
|
+150,000
|
New
|
|
|
17
|
Novo Holdings A/S
Hellerup,
Denmark
|
$510K
|
–
|
–
|
–
|
|
|
18
|
K2 Principal Fund
Toronto,
Ontario, Canada
|
$468K
|
+$470K
|
+59,747
|
+104%
|
|
|
19
|
|
$290K
|
+$569K
|
+72,400
|
New
|
|
|
20
|
State of New Jersey Common Pension Fund D
Trenton,
New Jersey
|
$260K
|
–
|
–
|
–
|
|
|
21
|
Royal Bank of Canada
Toronto,
Ontario, Canada
|
$225K
|
-$1.49M
|
-190,104
|
-77%
|
|
|
22
|
California Public Employees Retirement System
Sacramento,
California
|
$220K
|
–
|
–
|
–
|
|
|
23
|
Weiss Multi-Strategy Advisers
New York
|
$126K
|
–
|
–
|
–
|
|
|
24
|
Virtu KCG Holdings
New York
|
$122K
|
+$239K
|
+30,407
|
New
|
|
|
25
|
Scotia Capital
Toronto,
Ontario, Canada
|
$105K
|
+$42.3K
|
+5,385
|
+26%
|
|
