|
1
|
Avoro Capital Advisors
New York
|
$175M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$169M
|
+$1.37M
|
+37,020
|
+0.8%
|
|
|
3
|
Driehaus Capital Management
Chicago,
Illinois
|
$167M
|
-$993K
|
-26,872
|
-0.6%
|
|
|
4
|
Polar Capital Holdings
London,
United Kingdom
|
$108M
|
-$1.07M
|
-29,056
|
-1%
|
|
|
5
|
Capital International Investors
Los Angeles,
California
|
$83.1M
|
+$8.22M
|
+222,412
|
+11%
|
|
|
6
|
Marshall Wace
London,
United Kingdom
|
$83.1M
|
-$1.68M
|
-45,592
|
-2%
|
|
|
7
|
Capital World Investors
Los Angeles,
California
|
$81.4M
|
–
|
–
|
–
|
|
|
8
|
Braidwell
Stamford,
Connecticut
|
$76.5M
|
+$21.8M
|
+589,000
|
+38%
|
|
|
9
|
Pictet Asset Management (Switzerland)
Geneva 73,
Switzerland
|
$71.7M
|
-$4.26M
|
-115,322
|
-5%
|
|
|
10
|
Commodore Capital
New York
|
$66M
|
+$6.87M
|
+185,889
|
+11%
|
|
|
11
|
Perceptive Advisors
New York
|
$65.6M
|
-$3.29M
|
-89,099
|
-5%
|
|
|
12
|
BVF Inc
San Francisco,
California
|
$65.4M
|
+$20.6M
|
+556,715
|
+44%
|
|
|
13
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$63.8M
|
-$12.6M
|
-341,398
|
-16%
|
|
|
14
|
Redmile Group
San Francisco,
California
|
$47.5M
|
-$38.2M
|
-1,034,582
|
-44%
|
|
|
15
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$42.2M
|
+$86.1K
|
+2,330
|
+0.2%
|
|
|
16
|
|
$41.5M
|
-$1.29M
|
-34,820
|
-3%
|
|
|
17
|
|
$41.1M
|
–
|
–
|
–
|
|
|
18
|
Holocene Advisors
New York
|
$35.3M
|
-$7.59M
|
-205,443
|
-17%
|
|
|
19
|
Logos Global Management
San Francisco,
California
|
$32.2M
|
–
|
–
|
–
|
|
|
20
|
|
$32.2M
|
-$978K
|
-26,469
|
-3%
|
|
|
21
|
Citadel Advisors
Miami,
Florida
|
$31.2M
|
-$10.8M
|
-293,173
|
-25%
|
|
|
22
|
Great Point Partners
Greenwich,
Connecticut
|
$29.3M
|
-$1.16M
|
-31,495
|
-4%
|
|
|
23
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
$27.2M
|
+$3.08M
|
+83,402
|
+12%
|
|
|
24
|
Baker Bros. Advisors
New York
|
$26.9M
|
–
|
–
|
–
|
|
|
25
|
Adage Capital Partners
Boston,
Massachusetts
|
$26.8M
|
+$924K
|
+25,000
|
+3%
|
|
