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SPDR S&P Biotech ETF
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Overview Fund Activity

763 hedge funds and large institutions have $10.2B invested in SPDR S&P Biotech ETF in 2024 Q3 according to their latest regulatory filings, with 88 funds opening new positions, 238 increasing their positions, 269 reducing their positions, and 73 closing their positions.

Holders
763
Holders Change
+8
Holders Change %
+1.06%
% of All Funds
11.04%
Holding in Top 10
21
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+16.67%
% of All Funds
0.3%
New
88
Increased
238
Reduced
269
Closed
73
Calls
$2.8B
Puts
$3.33B
Net Calls
-$526M
Net Calls Change
+$836M

Top Buyers

1
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
1
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$912M
2
Morgan Stanley
2
Morgan Stanley
New York
$792M
3
CI
3
Clal Insurance
Israel
$141M
4
D.E. Shaw & Co
4
D.E. Shaw & Co
New York
$99.1M
5
Goldman Sachs
5
Goldman Sachs
New York
$1.26B

Top Sellers

1
ACA
1
Avoro Capital Advisors
New York
$0
2
Bank of America
2
Bank of America
North Carolina
$626M
3
BNP Paribas Financial Markets
3
BNP Paribas Financial Markets
France
$297M
4
Two Sigma Advisers
4
Two Sigma Advisers
New York
$18.6M
5
MMFA
5
Main Management Fund Advisors
California
$0
Name Market Value Shares Shares
Change 		Shares
Change %
CRM
776
Cramer Rosenthal McGlynn
Connecticut
– – -56,624 Closed
CCMG
777
Clark Capital Management Group
Pennsylvania
– – -46,488 Closed
LF
778
Longbow Finance
Switzerland
– – -44,256 Closed
AAA
779
Affinity Asset Advisors
New York
– – -37,550 Closed
BKA
780
Brick & Kyle Associates
Pennsylvania
– – -32,631 Closed
Capstone Investment Advisors
781
Capstone Investment Advisors
New York
– – -29,898 Closed
EE
782
EWG Elevate
California
– – -23,289 Closed
PA
783
Perceptive Advisors
New York
– – -22,665 Closed
LHWM
784
Lake Hills Wealth Management
Texas
– – -22,360 Closed
IMC Chicago
785
IMC Chicago
Illinois
– – -17,194 Closed
BCM
786
Bayesian Capital Management
New York
– – -17,100 Closed
QIM
787
Quantitative Investment Management
Virginia
– – -15,683 Closed
CAS
788
CTC Alternative Strategies
Illinois
– – -13,000 Closed
CSS
789
Cubist Systematic Strategies
Connecticut
– – -12,100 Closed
EL
790
Essex LLC
Illinois
– – -10,430 Closed
YIH
791
Y-Intercept (HK)
Hong Kong
– – -9,083 Closed
HHGC
792
Hunting Hill Global Capital
New York
– – -7,723 Closed
AGM
793
Alpine Global Management
New York
– – -6,599 Closed
GCM
794
Greenland Capital Management
New York
– – -6,365 Closed
Man Group
795
Man Group
United Kingdom
– – -6,190 Closed
SC
796
Searle & Co
Connecticut
– – -6,000 Closed
XS
797
XR Securities
Illinois
– – -5,872 Closed
CA
798
Calton & Associates
Florida
– – -5,527 Closed
CSPIA
799
Cary Street Partners Investment Advisory
Virginia
– – -5,182 Closed
PFA
800
Pinnacle Family Advisors
Missouri
– – -4,780 Closed
30 31
32
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