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State Street SPDR S&P Biotech ETF

656 hedge funds and large institutions have $12.4B invested in State Street SPDR S&P Biotech ETF in 2025 Q3 according to their latest regulatory filings, with 100 funds opening new positions, 151 increasing their positions, 243 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed

59% more first-time investments, than exits

New positions opened: 100 | Existing positions closed: 63

20% more funds holding in top 10

Funds holding in top 10: 1518 (+3)

16% more capital invested

Capital invested by funds: $10.7B → $12.4B (+$1.69B)

14.41% more ownership

Funds ownership: 200.2%214.61% (+14%)

5% more funds holding

Funds holding: 625656 (+31)

24% less call options, than puts

Call options by funds: $2.38B | Put options by funds: $3.15B

38% less repeat investments, than reductions

Existing positions increased: 151 | Existing positions reduced: 243

Holders
656
Holders Change
+31
Holders Change %
+4.96%
% of All Funds
8.61%
Holding in Top 10
18
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+20%
% of All Funds
0.24%
New
100
Increased
151
Reduced
243
Closed
63
Calls
$2.38B
Puts
$3.15B
Net Calls
-$772M
Net Calls Change
+$5.45M
Name Holding Trade Value Shares
Change
Change in
Stake
CI
26
Clal Insurance
Israel
$42.9M
IL
27
Investure LLC
Virginia
$41.3M -$13.5M -149,350 -27%
SO
28
STRS Ohio
Ohio
$40.6M +$2.26M +25,100 +7%
DCM
29
DAFNA Capital Management
California
$40.2M -$1.26M -14,000 -3%
Raymond James Financial
30
Raymond James Financial
Florida
$38.2M -$10.6M -117,859 -24%
ClearBridge Investments
31
ClearBridge Investments
New York
$36.1M -$33.8M -375,771 -51%
Stifel Financial
32
Stifel Financial
Missouri
$32.4M +$10.9M +120,768 +60%
SFS
33
Strategic Financial Services
New York
$28.6M +$341K +3,790 +1%
BlackRock
34
BlackRock
New York
$25.6M +$2.28M +25,280 +11%
SGH
35
Sivik Global Healthcare
Connecticut
$25.1M
MCM
36
Moore Capital Management
New York
$25.1M +$9.01M +100,000 +67%
Neuberger Berman Group
37
Neuberger Berman Group
New York
$24.8M -$432K -4,797 -2%
Allspring Global Investments
38
Allspring Global Investments
North Carolina
$24.3M +$9.73M +108,072 +81%
WT
39
Whittier Trust
California
$24.1M +$167K +1,855 +0.8%
GJL
40
Gendell Jeffrey L
$23.3M +$12.6M +140,000 +152%
Parallax Volatility Advisers
41
Parallax Volatility Advisers
California
$19.5M +$17.4M +192,958 +10,363%
UCMOK
42
United Capital Management of KS
Kansas
$18.9M +$377K +4,182 +2%
OPCM
43
Osborne Partners Capital Management
California
$18.8M +$154K +1,713 +0.9%
SSA
44
Schonfeld Strategic Advisors
New York
$17.8M +$14.4M +159,827 +892%
G
45
GenTrust
Florida
$17.6M -$1.2M -13,301 -7%
Rockefeller Capital Management
46
Rockefeller Capital Management
New York
$16.4M -$660K -7,333 -4%
EP
47
Ehrenkranz Partners
New York
$16.4M +$14.7M +163,193 New
VU
48
Vanderbilt University
Tennessee
$15.9M +$3.6K +40 +0%
WAM
49
Weatherly Asset Management
California
$15.6M -$68.5K -760 -0.5%
Cetera Investment Advisers
50
Cetera Investment Advisers
Illinois
$15.4M -$367K -4,073 -3%