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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

731 hedge funds and large institutions have $9.85B invested in SPDR S&P Biotech ETF in 2024 Q4 according to their latest regulatory filings, with 101 funds opening new positions, 193 increasing their positions, 280 reducing their positions, and 115 closing their positions.

Holders
731
Holders Change
-32
Holders Change %
-4.19%
% of All Funds
9.74%
Holding in Top 10
16
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-23.81%
% of All Funds
0.21%
New
101
Increased
193
Reduced
280
Closed
115
Calls
$2.07B
Puts
$3.32B
Net Calls
-$1.26B
Net Calls Change
-$729M

Top Buyers

1
BNP Paribas Financial Markets
1
BNP Paribas Financial Markets
France
$1.07B
2
Citigroup
2
Citigroup
New York
$1B
3
Bank of America
3
Bank of America
North Carolina
$767M
4
Morgan Stanley
4
Morgan Stanley
New York
$916M
5
UBS Group
5
UBS Group
Switzerland
$322M

Top Sellers

1
JPMorgan Chase & Co
1
JPMorgan Chase & Co
New York
$721M
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$465M
3
Goldman Sachs
3
Goldman Sachs
New York
$861M
4
CI Investments Inc
4
CI Investments Inc
Ontario, Canada
$6.66M
5
CI
5
Clal Insurance
Israel
$48.1M
Name Market Value Shares Shares
Change 		Shares
Change %
ClearBridge Investments
26
ClearBridge Investments
New York
$51.5M 571,664 +97,401 +21%
IL
27
Investure LLC
Virginia
$50.6M 561,600 – –
CI
28
Clal Insurance
Israel
$48.1M 534,000 -896,000 -63%
Royal Bank of Canada
29
Royal Bank of Canada
Ontario, Canada
$44.4M 492,592 -453,293 -48%
BlackRock
30
BlackRock
New York
$43M 477,738 +40,909 +9%
Twin Tree Management
31
Twin Tree Management
Texas
$40.8M 452,758 +238,603 +111%
Thrivent Financial for Lutherans
32
Thrivent Financial for Lutherans
Minnesota
$40.1M 444,800 -68,786 -13%
DCM
33
DAFNA Capital Management
California
$35.8M 397,505 -4,000 -1%
Barclays
34
Barclays
United Kingdom
$35M 388,389 -134,181 -26%
DFG
35
Demars Financial Group
Washington
$34.6M 3,112,474 +3,112,474 New
D.E. Shaw & Co
36
D.E. Shaw & Co
New York
$33.6M 373,427 -629,378 -63%
O
37
OrbiMed
New York
$33.5M 372,000 +372,000 New
Susquehanna International Group
38
Susquehanna International Group
Pennsylvania
$33M 365,894 +160,040 +78%
SO
39
STRS Ohio
Ohio
$30.9M 342,800 -77,500 -18%
Brown Advisory
40
Brown Advisory
Maryland
$29.6M 328,220 -687,813 -68%
WT
41
Whittier Trust
California
$28.9M 320,740 +9,713 +3%
Parallax Volatility Advisers
42
Parallax Volatility Advisers
California
$28.5M 316,006 +263,782 +505%
VOYA Investment Management
43
VOYA Investment Management
Georgia
$28.1M 312,263 +6,087 +2%
Simplex Trading
44
Simplex Trading
Illinois
$27.3M 302,694 +302,694 New
JSAM
45
J. Safra Asset Management
New York
$26.3M 292,502 +240,415 +462%
Neuberger Berman Group
46
Neuberger Berman Group
New York
$23.2M 257,590 -2,077 -0.8%
HCMG
47
Howard Capital Management Group
California
$22.9M 254,166 +6,052 +2%
ITP
48
Iron Triangle Partners
Connecticut
$22.5M 250,000 +250,000 New
Bank of Montreal
49
Bank of Montreal
Ontario, Canada
$22.4M 248,589 +4,793 +2%
SFS
50
Strategic Financial Services
New York
$22.4M 248,521 +5,079 +2%
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