UPB

Upstream Bio, Inc. Common Stock
UPB

Overview Fund Activity

70 hedge funds and large institutions have $690M invested in Upstream Bio, Inc. Common Stock in 2024 Q4 according to their latest regulatory filings, with 70 funds opening new positions, increasing their positions, reducing their positions, and closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
70
Holders Change
+70
Holders Change %
–
% of All Funds
0.93%
Holding in Top 10
6
Holding in Top 10 Change
+6
Holding in Top 10 Change %
%
% of All Funds
0.08%
New
70
Increased
–
Reduced
–
Closed
–
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
Fidelity Investments
1
Fidelity Investments
Massachusetts
$118M
2
O
2
OrbiMed
New York
$93.6M
3
DC
3
Decheng Capital
California
$54M
4
TCM
4
TCG Crossover Management
California
$44.9M
5
BCLSI
5
Bain Capital Life Sciences Investors
Massachusetts
$37.7M

Top Sellers

No sellers this quarter
Name Holding Trade Value Shares
Change 		Shares
Change %
Mirae Asset Global ETFs Holdings
51
Mirae Asset Global ETFs Holdings
Hong Kong
$162K +$162K +9,828 New
Wells Fargo
52
Wells Fargo
California
$149K +$149K +9,047 New
CF
53
Corebridge Financial
Texas
$142K +$142K +8,660 New
SG Americas Securities
54
SG Americas Securities
New York
$125K +$125K +7,590 New
SO
55
STRS Ohio
Ohio
$52.6K +$52.6K +3,200 New
TRCT
56
Tower Research Capital (TRC)
New York
$46.8K +$46.8K +2,846 New
AIP
57
Ameritas Investment Partners
Nebraska
$30K +$30K +1,822 New
Legal & General Group
58
Legal & General Group
United Kingdom
$28.5K +$28.5K +1,734 New
US Bancorp
59
US Bancorp
Minnesota
$27.3K +$27.3K +1,660 New
BNP Paribas Financial Markets
60
BNP Paribas Financial Markets
France
$24.8K +$24.8K +1,511 New
California State Teachers Retirement System (CalSTRS)
61
California State Teachers Retirement System (CalSTRS)
California
$21.2K +$21.2K +1,290 New
Royal Bank of Canada
62
Royal Bank of Canada
Ontario, Canada
$21K +$21K +1,282 New
AB
63
Amalgamated Bank
New York
$10K +$10K +594 New
SCM
64
Sterling Capital Management
North Carolina
$4.09K +$4.09K +249 New
RS
65
R Squared
Hong Kong
$2.63K +$2.63K +160 New
ACM
66
Aster Capital Management
United Arab Emirates
$2.2K +$2.2K +134 New
CIAM
67
Caitong International Asset Management
Hong Kong
$723 +$723 +44 New
Osaic Holdings
68
Osaic Holdings
Arizona
$279 +$279 +17 New
PS
69
Principal Securities
Iowa
$197 +$197 +12 New
National Bank of Canada
70
National Bank of Canada
Quebec, Canada
$115 +$115 +7 New
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