Wells Fargo
UPB

Wells Fargo’s Upstream Bio Inc UPB Stock Holding History

Wells Fargo’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$166K Sell
18,402
-18,392
-50% -$331K ﹤0.01% 4822
2025
Q4 		$999K Buy
36,794
+11,634
+46% +$290K ﹤0.01% 3971
2025
Q3 		$473K Buy
25,160
+2,796
+13% +$43.4K ﹤0.01% 4341
2025
Q2 		$246K Buy
22,364
+13,114
+142% +$121K ﹤0.01% 4651
2025
Q1 		$56.6K Buy
9,250
+203
+2% +$1.94K ﹤0.01% 5357
2024
Q4 		$149K Buy
+9,047
New +$202K ﹤0.01% 4968

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $661M AUM 299.97% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $352M AUM 220.14% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
YIH
Y-Intercept (HK) Hong Kong $5.05B AUM 17.89% 1-Year Est. Return
Federated Hermes
Federated Hermes Pittsburgh, Pennsylvania $61.5B AUM 30.7% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return

Wells Fargo's UPB Position: Q1 2026 in Review

Wells Fargo reduced its Upstream Bio Inc (UPB) stake by 50% in Q1 2026, selling an estimated $331K and leaving 18,402 shares worth $166K. The position accounts for ﹤0.01% of the portfolio, ranked #4822.

Wells Fargo first reported a position in UPB in Q4 2024 and has held it in 6 quarters since. The position peaked at $999K in Q4 2025. 140 funds tracked by Wall St. Rank hold UPB as of Q1 2026.

  • Wells Fargo held 18,402 shares of Upstream Bio Inc worth $166K as of Q1 2026.
  • Wells Fargo sold 18,392 Upstream Bio Inc shares in Q1 2026, an estimated $331K.
  • Upstream Bio Inc made up ﹤0.01% of Wells Fargo's portfolio in Q1 2026, its #4822 holding.
  • Wells Fargo first reported a position in Upstream Bio Inc in Q4 2024 and has held it in 6 quarters since.
  • Wells Fargo's Upstream Bio Inc position peaked at $999K in Q4 2025.
  • 140 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q1 2026.

Based on Wells Fargo's 13F filing for Q1 2026, filed 11 May 2026.