Wells Fargo
UPB

Wells Fargo’s Upstream Bio Inc UPB Stock Holding History

Wells Fargo’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$204K Buy
29,497
+11,095
+60% +$93K ﹤0.01% 5195
2026
Q1 		$166K Sell
18,402
-18,392
-50% -$331K ﹤0.01% 4822
2025
Q4 		$999K Buy
36,794
+11,634
+46% +$290K ﹤0.01% 3971
2025
Q3 		$473K Buy
25,160
+2,796
+13% +$43.4K ﹤0.01% 4341
2025
Q2 		$246K Buy
22,364
+13,114
+142% +$121K ﹤0.01% 4651
2025
Q1 		$56.6K Buy
9,250
+203
+2% +$1.94K ﹤0.01% 5357
2024
Q4 		$149K Buy
+9,047
New +$202K ﹤0.01% 4968

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
O
OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return
Norges Bank
Norges Bank Oslo, Norway $1T AUM
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $732M AUM 275.56% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $345M AUM 134.64% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Millennium Management
Millennium Management New York $276B AUM 44.8% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $210B AUM 57.28% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return

Wells Fargo's UPB Position: Q2 2026 in Review

Wells Fargo increased its Upstream Bio Inc (UPB) stake by 60% in Q2 2026, buying an estimated $93K and bringing the position to 29,497 shares worth $204K. The position accounts for ﹤0.01% of the portfolio, ranked #5195.

Wells Fargo first reported a position in UPB in Q4 2024 and has held it in 7 quarters since. The position peaked at $999K in Q4 2025. 148 funds tracked by Wall St. Rank hold UPB as of Q2 2026.

  • Wells Fargo held 29,497 shares of Upstream Bio Inc worth $204K as of Q2 2026.
  • Wells Fargo bought 11,095 Upstream Bio Inc shares in Q2 2026, an estimated $93K.
  • Upstream Bio Inc made up ﹤0.01% of Wells Fargo's portfolio in Q2 2026, its #5195 holding.
  • Wells Fargo first reported a position in Upstream Bio Inc in Q4 2024 and has held it in 7 quarters since.
  • Wells Fargo's Upstream Bio Inc position peaked at $999K in Q4 2025.
  • 148 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q2 2026.

Based on Wells Fargo's 13F filing for Q2 2026, filed 14 Aug 2026.