SG Americas Securities
UPB

SG Americas Securities’s Upstream Bio Inc UPB Stock Holding History

SG Americas Securities’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$141K Buy
+20,338
New +$170K ﹤0.01% 2950
2026
Q1 		– Sell
-5,518
Closed -$150K – 3801
2025
Q4 		$150K Buy
+5,518
New +$137K ﹤0.01% 3045
2025
Q1 		– Sell
-7,590
Closed -$125K – 3827
2024
Q4 		$125K Buy
+7,590
New +$169K ﹤0.01% 2567

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
O
OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return
Norges Bank
Norges Bank Oslo, Norway $1T AUM
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $732M AUM 275.56% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $345M AUM 134.64% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Millennium Management
Millennium Management New York $276B AUM 44.8% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $210B AUM 57.28% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return

SG Americas Securities's UPB Position: Q2 2026 in Review

SG Americas Securities opened a new position in Upstream Bio Inc (UPB) in Q2 2026: 20,338 shares worth $141K. The stake represents ﹤0.01% of the portfolio and ranks #2950 among its holdings. This is a return to the name: SG Americas Securities previously reported a position in UPB as recently as Q4 2025.

SG Americas Securities first reported a position in UPB in Q4 2024 and has held it in 3 quarters since. The position peaked at $150K in Q4 2025. 148 funds tracked by Wall St. Rank hold UPB as of Q2 2026.

  • SG Americas Securities held 20,338 shares of Upstream Bio Inc worth $141K as of Q2 2026.
  • Upstream Bio Inc was a new SG Americas Securities position in Q2 2026.
  • Upstream Bio Inc made up ﹤0.01% of SG Americas Securities's portfolio in Q2 2026, its #2950 holding.
  • SG Americas Securities first reported a position in Upstream Bio Inc in Q4 2024 and has held it in 3 quarters since.
  • SG Americas Securities's Upstream Bio Inc position peaked at $150K in Q4 2025.
  • 148 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q2 2026.

Based on SG Americas Securities's 13F filing for Q2 2026, filed 7 Aug 2026.