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Tyra Biosciences
TYRA

Overview Fund Activity

121 hedge funds and large institutions have $542M invested in Tyra Biosciences in 2025 Q2 according to their latest regulatory filings, with 18 funds opening new positions, 61 increasing their positions, 21 reducing their positions, and 14 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
121
Holders Change
+4
Holders Change %
+3.42%
% of All Funds
1.62%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.04%
New
18
Increased
61
Reduced
21
Closed
14
Calls
$1K
Puts
–
Net Calls
+$1K
Net Calls Change
-$182K

Top Buyers

1
CC
Commodore Capital
New York
$29.7M
2
RCM
RA Capital Management
Massachusetts
$117M
3
SCM
Sio Capital Management
New York
$7.75M
4
Balyasny Asset Management
Balyasny Asset Management
Illinois
$5.58M
5
Bank of America
Bank of America
North Carolina
$3.57M

Top Sellers

1
Fidelity Investments
Fidelity Investments
Massachusetts
$117K
2
O
OrbiMed
New York
$7.7M
3
CPX
Canaan Partners XI
California
$34.5M
4
Pictet Asset Management
Pictet Asset Management
Switzerland
$0
5
VPC
Vestal Point Capital
New York
$25.4M
Name Holding Trade Value Shares
Change 		Shares
Change %
Jane Street
51
Jane Street
New York
$557K +$224K +23,355 +67%
Bank of New York Mellon
52
Bank of New York Mellon
New York
$517K +$124K +12,956 +32%
SPS
53
Susquehanna Portfolio Strategies
Pennsylvania
$466K +$466K +48,644 New
UBS Group
54
UBS Group
Switzerland
$443K -$172 -18 -0%
TI
55
Trexquant Investment
Connecticut
$428K +$428K +44,681 New
Victory Capital Management
56
Victory Capital Management
Texas
$423K -$114K -11,960 -21%
PP
57
PDT Partners
New York
$414K +$414K +43,310 New
Dimensional Fund Advisors
58
Dimensional Fund Advisors
Texas
$399K +$66.7K +6,969 +20%
Verition Fund Management
59
Verition Fund Management
Connecticut
$392K -$11.8K -1,235 -3%
RhumbLine Advisers
60
RhumbLine Advisers
Massachusetts
$389K +$121K +12,604 +45%
Susquehanna International Group
61
Susquehanna International Group
Pennsylvania
$362K +$136K +14,256 +61%
BHCM
62
Brevan Howard Capital Management
Jersey
$350K -$93.6K -9,777 -21%
AllianceBernstein
63
AllianceBernstein
Tennessee
$341K +$173K +18,070 +103%
XT
64
XTX Topco
Cayman Islands
$331K +$331K +34,601 New
DTL
65
Dynamic Technology Lab
Singapore
$326K +$326K +34,115 New
Squarepoint
66
Squarepoint
New York
$301K +$301K +31,408 New
American Century Companies
67
American Century Companies
Missouri
$276K +$51.9K +5,423 +23%
AA
68
ALPS Advisors
Colorado
$275K +$275K +28,729 New
AQR Capital Management
69
AQR Capital Management
Connecticut
$275K +$275K +28,712 New
Tudor Investment Corp
70
Tudor Investment Corp
Connecticut
$251K +$136K +14,172 +117%
HS
71
HighVista Strategies
Massachusetts
$239K +$9.77K +1,021 +4%
CC
72
Corton Capital
Ontario, Canada
$233K +$233K +24,346 New
AI
73
Auour Investments
Massachusetts
$201K – – –
IIM
74
INTECH Investment Management
Florida
$191K +$60.5K +6,322 +46%
Ohio Public Employees Retirement System (OPERS)
75
Ohio Public Employees Retirement System (OPERS)
Ohio
$177K +$177K +18,512 New
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3
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