Jane Street’s Tyra Biosciences TYRA Stock Holding History

Jane Street’s Portfolio TYRA Stock Details TYRA Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$389K	Buy	+10,169	New	+$329K	﹤0.01%	8612
2025 Q4	–	Sell	-44,680	Closed	-$625K	–	12427
2025 Q3	$625K	Sell	44,680 -13,488	-23%	-$154K	﹤0.01%	7362
2025 Q2	$557K	Buy	58,168 +23,355	+67%	+$222K	﹤0.01%	6715
2025 Q1	$324K	Buy	+34,813	New	+$450K	﹤0.01%	7674
2024 Q4	–	Sell	-31,003	Closed	-$729K	–	10630
2024 Q3	$729K	Sell	31,003 -9,995	-24%	-$210K	﹤0.01%	6535
2024 Q2	$656K	Buy	+40,998	New	+$706K	﹤0.01%	6575

Other funds holding TYRA

RCM

RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

Nextech Invest Zurich, Switzerland $1.42B AUM 304.47% 1-Year Est. Return

Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return

APMC

Alta Partners Management Company Jackson, Wyoming $127M AUM 230.85% 1-Year Est. Return

FCM

Farallon Capital Management San Francisco, California $17.5B AUM 50.95% 1-Year Est. Return

TCM

TCG Crossover Management Palo Alto, California $3.5B AUM 1,165.83% 1-Year Est. Return

Commodore Capital New York $1.73B AUM 298.96% 1-Year Est. Return

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

PBA

Paradigm Biocapital Advisors New York $4.89B AUM 251.12% 1-Year Est. Return

Jane Street's TYRA Position: Q1 2026 in Review

Jane Street opened a new position in Tyra Biosciences (TYRA) in Q1 2026: 10,169 shares worth $389K. The stake represents ﹤0.01% of the portfolio and ranks #8612 among its holdings. This is a return to the name: Jane Street previously reported a position in TYRA as recently as Q3 2025.

Jane Street first reported a position in TYRA in Q2 2024 and has held it in 6 quarters since. The position peaked at $729K in Q3 2024. 164 funds tracked by Wall St. Rank hold TYRA as of Q1 2026.

Jane Street held 10,169 shares of Tyra Biosciences worth $389K as of Q1 2026.
Tyra Biosciences was a new Jane Street position in Q1 2026.
Tyra Biosciences made up ﹤0.01% of Jane Street's portfolio in Q1 2026, its #8612 holding.
Jane Street first reported a position in Tyra Biosciences in Q2 2024 and has held it in 6 quarters since.
Jane Street's Tyra Biosciences position peaked at $729K in Q3 2024.
164 funds tracked by Wall St. Rank held Tyra Biosciences as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.