Squarepoint
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Squarepoint’s Tyra Biosciences TYRA Stock Holding History

Squarepoint’s Portfolio TYRA Stock Details TYRA Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$785K Sell
20,494
-33,930
-62% -$1.1M ﹤0.01% 2978
2025
Q4 		$1.43M Buy
54,424
+42,210
+346% +$775K ﹤0.01% 2315
2025
Q3 		$171K Sell
12,214
-19,194
-61% -$219K ﹤0.01% 3989
2025
Q2 		$301K Buy
+31,408
New +$298K ﹤0.01% 3683
2025
Q1 		– Sell
-18,216
Closed -$253K – 5431
2024
Q4 		$253K Buy
+18,216
New +$331K ﹤0.01% 4287

Other funds holding TYRA

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
NI
Nextech Invest Zurich, Switzerland $1.42B AUM 304.47% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
APMC
Alta Partners Management Company Jackson, Wyoming $151M AUM 296.21% 1-Year Est. Return
FCM
Farallon Capital Management San Francisco, California $17.5B AUM 50.95% 1-Year Est. Return
TCM
TCG Crossover Management Palo Alto, California $3.5B AUM 1,165.83% 1-Year Est. Return
CC
Commodore Capital New York $1.73B AUM 298.96% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
PBA
Paradigm Biocapital Advisors New York $4.89B AUM 251.12% 1-Year Est. Return

Squarepoint's TYRA Position: Q1 2026 in Review

Squarepoint reduced its Tyra Biosciences (TYRA) stake by 62% in Q1 2026, selling an estimated $1.1M and leaving 20,494 shares worth $785K. The position accounts for ﹤0.01% of the portfolio, ranked #2978.

Squarepoint first reported a position in TYRA in Q4 2024 and has held it in 5 quarters since. The position peaked at $1.43M in Q4 2025. 164 funds tracked by Wall St. Rank hold TYRA as of Q1 2026.

  • Squarepoint held 20,494 shares of Tyra Biosciences worth $785K as of Q1 2026.
  • Squarepoint sold 33,930 Tyra Biosciences shares in Q1 2026, an estimated $1.1M.
  • Tyra Biosciences made up ﹤0.01% of Squarepoint's portfolio in Q1 2026, its #2978 holding.
  • Squarepoint first reported a position in Tyra Biosciences in Q4 2024 and has held it in 5 quarters since.
  • Squarepoint's Tyra Biosciences position peaked at $1.43M in Q4 2025.
  • 164 funds tracked by Wall St. Rank held Tyra Biosciences as of Q1 2026.

Based on Squarepoint's 13F filing for Q1 2026, filed 15 May 2026.