SEPN

Septerna Inc

124 hedge funds and large institutions have $1.1B invested in Septerna Inc in 2026 Q1 according to their latest regulatory filings, with 28 funds opening new positions, 43 increasing their positions, 30 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
124
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$1.81M
Puts
Net Calls
Net Calls Change

Top Buyers

1 +$23.4M
2 +$13.2M
3 +$6.13M
4
Goldman Sachs
Goldman Sachs
New York
+$5.03M
5
FLAM
First Light Asset Management
Minnesota
+$2.95M

Top Sellers

1 -$12.1M
2 -$10.9M
3 -$10.7M
4
BI
BVF Inc
California
-$9.66M
5
Marshall Wace
Marshall Wace
United Kingdom
-$4.92M
Name Holding Trade Value Shares
Change
Change in
Stake
Carson Wealth (CWM LLC)
101
Carson Wealth (CWM LLC)
Nebraska
$21.5K
Nisa Investment Advisors
102
Nisa Investment Advisors
Missouri
$20.2K
TRCT
103
Tower Research Capital (TRC)
New York
$17.2K
SCM
104
Sterling Capital Management
North Carolina
$17.1K
Zurich Cantonal Bank
105
Zurich Cantonal Bank
Switzerland
$12.2K
PWPS
106
Pinnacle Wealth Planning Services
Ohio
$7.74K
VCM
107
Versant Capital Management
Arizona
$6.27K
LFG
108
Larson Financial Group
Missouri
$4.9K
DP
109
Diadema Partners
New Jersey
$4.85K
US Bancorp
110
US Bancorp
Minnesota
$4.73K
NEWAS
111
N.E.W. Advisory Services
Wisconsin
$4.33K
UBS AM
112
UBS AM
Illinois
$3.73K
MPWT
113
MassMutual Private Wealth & Trust
Connecticut
$3.24K
EWA
114
EverSource Wealth Advisors
Alabama
$1.63K
SS
115
SBI Securities
Japan
$1.32K
CFM
116
Cornerstone Financial Management
Massachusetts
$1.25K
PNC Financial Services Group
117
PNC Financial Services Group
Pennsylvania
$1.03K
CIAM
118
Caitong International Asset Management
Hong Kong
$913
RIL
119
Rothschild Investment LLC
Illinois
$721
FFO
120
Fortitude Family Office
Arizona
$481
AF
121
Allworth Financial
California
$409
FFA
122
Farther Finance Advisors
California
$171
QCG
123
Quadrant Capital Group
Ohio
$169
MCM
124
MAI Capital Management
Ohio
$145
PA
125
Perceptive Advisors
New York