SEPN

Septerna Inc

124 hedge funds and large institutions have $1.1B invested in Septerna Inc in 2026 Q1 according to their latest regulatory filings, with 28 funds opening new positions, 43 increasing their positions, 30 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
124
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$1.81M
Puts
Net Calls
Net Calls Change

Top Buyers

1 +$23.4M
2 +$13.2M
3 +$6.13M
4
Goldman Sachs
Goldman Sachs
New York
+$5.03M
5
FLAM
First Light Asset Management
Minnesota
+$2.95M

Top Sellers

1 -$12.1M
2 -$10.9M
3 -$10.7M
4
BI
BVF Inc
California
-$9.66M
5
Marshall Wace
Marshall Wace
United Kingdom
-$4.92M
Name Holding Trade Value Shares
Change
Change in
Stake
CUAMC
76
China Universal Asset Management Company
China
$287K
Man Group
77
Man Group
United Kingdom
$285K
Russell Investments Group
78
Russell Investments Group
United Kingdom
$277K
SFCM
79
Seven Fleet Capital Management
California
$275K
VIA
80
Virtus Investment Advisers
Connecticut
$258K
Massachusetts Financial Services
81
Massachusetts Financial Services
Massachusetts
$249K
Mirae Asset Global ETFs Holdings
82
Mirae Asset Global ETFs Holdings
Hong Kong
$241K
Wells Fargo
83
Wells Fargo
California
$237K
Citigroup
84
Citigroup
New York
$221K
WG
85
Winton Group
United Kingdom
$212K
VAM
86
Vanguard Asset Management
$178K
Legal & General Group
87
Legal & General Group
United Kingdom
$138K
New York State Common Retirement Fund
88
New York State Common Retirement Fund
New York
$135K
BNP Paribas Financial Markets
89
BNP Paribas Financial Markets
France
$129K
PFSRSONJ
90
Police & Firemen's Retirement System of New Jersey
New Jersey
$124K
VIA
91
Vanguard Investments Australia
Australia
$93.6K
Ohio Public Employees Retirement System (OPERS)
92
Ohio Public Employees Retirement System (OPERS)
Ohio
$81.1K
KK
93
KLP Kapitalforvaltning
Norway
$60.1K
Mirae Asset Global Investments
94
Mirae Asset Global Investments
South Korea
$56.1K
C
95
Covestor
United Kingdom
$54K
AIP
96
Ameritas Investment Partners
Nebraska
$46.7K
California State Teachers Retirement System (CalSTRS)
97
California State Teachers Retirement System (CalSTRS)
California
$27.8K
GI
98
GAMMA Investing
California
$26.7K
GFM
99
GF Fund Management
China
$24.2K
S
100
SignatureFD
Georgia
$23.2K